Chromium- Urine Random

Chromium is a naturally occurring metal found in a variety of oxidative states. Among these, trivalent chromium and hexavalent chromium are the most abundant forms and play an impactful role in human health.

Trivalent chromium is associated with low toxicity. It is present in the human body in small quantities and aids in regulating the metabolism of fats and sugars. It is often ingested in the form of food items or supplements and may enhance overall human health.

On the contrary, hexavalent chromium is toxic in nature and released into the environment due to human activities. These activities include the welding and cutting of stainless steel.

The human body is exposed to chromium by inhalation, ingestion, or direct contact. Airborne exposure to hexavalent chromium is usually due to tobacco smoke, especially if smoking in an enclosed space.

Some complications that arise due to excess chromium exposure are:

• Pulmonary sensitization
• Increased chances of lung, sinus, or nose cancer
• Severe dermatitis
• Painless skin ulcers

Due to these complications, it is vital to get a chromium-urine random test performed. This test helps in determining the unhealthy levels of chromium in the body. It also indicates if the exposure is long-term or short-term.

In addition, doctors also recommend this test for individuals with prosthetic implants to determine the level of wear.

The procedure of the chromium-urine random test is standard. The patient is asked to collect a random urine sample for testing, usually at the start of the day. The specimen is then analysed, and the results help determine chromium poisoning. Since chromium is mainly excreted through urine, it is a more reliable method of gauging the levels.

The expected results for this test are:

• If the chromium levels in the urine are less than 2 ng/ml (nanograms per millilitre), it may be safe to presume the absence of excess chromium.
• The chromium to creatinine levels should be less than 0.8:1 to rule out chromium poisoning.

Since normal urine has a low level of creatinine, an increase could point toward external contamination.

Apollo 24|7 offers a chromium-urine random test that may address the following symptoms:

• Irritation to the nose and throat
• Development of sores in the nose
• Nosebleeds
• Formation of a red, itchy rash that may turn crusty and thickened without medical attention

If these symptoms are persistent or turn severe, a doctor can help better and recommend some tests to confirm a diagnosis. Although there is no antidote for chromium poisoning, there are multiple treatment methods based on the severity of the symptoms and the mode of exposure.

Medically reviewed by Dr. P Siva Charan Reddy, Surgical gastroenterologist, Apollo Hospitals Jubilee Hills, Hyderabad.