CD1A (Pan T Cell Marker)

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    blood sample




    Age group

    Above 10 years

    The cluster of differentiation (CD) refers to proteins that are expressed on the surface of the cells of the immune system. For ease of identification, each surface molecule has a different number that plays a unique role in the immune system. The CD1A protein is the first member of the CD1 system. It plays the role of a marker for dendritic cells and is mainly known as a protein-coding gene. Evaluation of CD1A T cells helps detect a wide variety of diseases. For this purpose, a CD1A Pan T-cell marker test proves helpful.

    The analysis of the CD1A expression helps detect the following:

    • Langerhans cells
    • Immature T cells

    The CD1A function can also prove helpful in marking cortical thymocytes. Following are some diseases associated with specific markers like CD1A:

    • Histiocytosis
    • Langerhans cells histiocytosis

    In these conditions, histiocytes, a group of white blood cells (WBCs), accumulate in one or more of the following parts or organs:

    • Spleen
    • Liver
    • Lymph nodes
    • Skin
    • Bones

    This condition can cause damage to the tissues and lead to benign or malignant tumours. On the other hand, Langerhans cells histiocytosis is a disease that can lead to lesions in multiple places of the body. This illness is primarily a case of genetic mutation. Hence, your doctor can recommend the CD1A Pan T-cell marker test to detect such rare diseases.

    The medical testing of CD1A protein is done either through the analysis of blood or tissue sample. In most cases, a blood sample can be sufficient to study the CD1A expression and levels. During the test, a lab technician can use the process of venepuncture. The professional can draw blood from a vein on your arm during this process. Hence, you might face mild pain or irritation at the site of needle entry.

    Before testing CD1A T cells, the medical lab may require your clinical history. This data is necessary for determining the influence of various factors on CD1A expression and the behaviour of specific markers.

    You do not need to fast before providing the blood or tissue sample. The family members of CD1 can differ in their cellular localisation. Hence, the testing requires in-depth analysis.

    At Apollo 24|7, you can get the CD1A Pan T-cell marker test done at reasonable rates. We ensure a detailed analysis of your results primarily within three days.

    Medically reviewed by Dr. Sanjaya Kumar Mishra, radiation oncologist from Apollo Hospitals Old Sainik School Road,Bhubaneswar.

    faqFrequently Asked Questions (FAQs)

    Frequently asked questions

    The cluster of differentiation 1A (CD1A) protein has its expression on dendritic cells, Langerhans cells, and thymocytes. This class of molecules occur in the peripheral nerve of the inflammatory system. The CD1 molecule is a useful phenotypic marker of various cells. Notably, some CD1A T cells recognise foreign antigens.
    The Langerhans cells reside in the epidermis in the form of an immune system sentinel network. They are useful in determining abilities like inflammatory and tolerance responses to foreign substances. Langerhans cells work by interpreting microenvironmental context.
    Usually, your doctor suggests blood tests, computed tomography (CT) scans or X-rays to detect Langerhans cell histiocytosis. This condition can impact the bones and can lead to benign or malignant tumours. Hence, a bone X-ray can prove helpful in interpreting the result.
    The CD1 molecules present lipid antigens to the T cells. These molecules represent a wide array of antigen classes ranging from foreign lipids to the well-known mammalian self-lipids. Some of the common lipids that CD1 presents are phospholipids, polyketides, ceramides, sulpholipids, and gangliosides.
    Yes, Langerhans cells are WBCs that flow all over your body. They are present in areas like bone marrow, lymph nodes, mouth, spleen, pituitary glands, and skin. In addition, they are also present in the central nervous system.
    T cells, also known as T lymphocytes, are vital facets of your immune system. They are responsible for killing infected host cells and boosting your body's immune response. T cells also help produce cytokines that act as humoral regulators, which play a crucial part in modulating various functions of cells. They are crucial to regulating the overall response of your body’s immune system.

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    The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results