CD58 (Pnh Marker)

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    blood sample




    Age group

    Above 10 years

    CD58 is a protein present on the surface of white blood cells. The CD58 (Pnh Marker) panel test is a flow cytometry-based diagnostic test that measures the expression of CD58 on the surface of red blood cells.

    It helps to diagnose paroxysmal nocturnal hemoglobinuria (PNH), which is a rare blood disorder that causes the breakdown of red blood cells leading to anaemia, blood clots, and other complications.


    PNH is a rare blood disorder that can be difficult to diagnose as its symptoms overlap with several other conditions. The following are some common symptoms associated with PNH:
    - Fatigue
    - Shortness of breath
    - Chest pain
    - Blood clots
    - Abdominal pain
    - Difficulty swallowing
    - Headache
    - Back pain
    - Dark urine

    Test Procedure

    The CD58 (Pnh Marker) panel test requires a bone marrow sample. The bone marrow sample is collected using a needle that is inserted into the pelvic or breastbone. The process can be painful, but it is generally safe and has few risks. After the sample is collected, it is sent to the lab for analysis.

    The CD58 (Pnh Marker) panel test is a flow cytometry-based test that measures the expression of CD58 on the surface of red blood cells. During the test, a small amount of bone marrow samples is mixed with fluorescently labelled antibodies specific to different cell markers. The mixture is then analysed using a flow cytometer, which measures the fluorescence intensity of each cell. Based on the intensity of fluorescence, the number of CD58-positive cells is determined.


    There is no cure for PNH. There are certain treatments that can help manage the symptoms and improve the quality of life for patients. The treatment options may include blood transfusions, anticoagulant therapy, bone marrow transplant, and medication.

    Booking a CD58 (Pnh Marker) Panel on Apollo 24|7

    Booking a CD58 (Pnh Marker) panel on Apollo 24|7 is easy and convenient. Simply visit the Apollo 24|7 website and select the “Lab Tests” option from the menu. From there, you can search for the test by name and select your preferred location and time slot. Results for the CD58 (Pnh Marker) panel are typically available within 72 hours, allowing for prompt diagnosis and treatment if necessary.

    Benefits of Early Diagnosis

    Early diagnosis of PNH through the CD58 (Pnh Marker) panel can be highly beneficial. Some advantages of early diagnosis include:
    1. Accurate diagnosis and treatment
    2. Improved quality of life
    3. Reduced risk of complications
    4. Better management of symptoms

    If you suspect that you have PNH or have been diagnosed with aplastic anaemia or myelodysplastic syndrome, it is recommended that you get tested for PNH. You can book the CD58 (Pnh Marker) panel test on Apollo 24|7 at an affordable price. Early diagnosis and treatment can help manage the symptoms and improve the quality of life for patients with PNH. Additionally, individuals who opt for early diagnosis can also benefit from the accuracy of the method and avoid complications associated with late diagnosis.

    faqFrequently Asked Questions (FAQs)

    Frequently asked questions

    PNH is caused by a genetic mutation that affects the production of proteins responsible for protecting red blood cells from destruction.
    PNH is not inherited; it occurs as a result of a spontaneous gene mutation.
    PNH does not cause cancer, but people with PNH are at an increased risk of developing certain types of cancer.
    The bone marrow biopsy used to collect the sample can be painful, but the procedure is generally safe and has few risks.
    The CD58 (Pnh Marker) panel test is highly accurate and reliable for diagnosing PNH. However, like any other test, it is not 100% accurate. A negative result does not always rule out PNH, and a positive result may require additional tests for confirmation.

    Why should Apollo be your preferred healthcare partner?

    • 40 Years of legacy and credibility in the healthcare industry.
    • NABL certified multi-channel digital healthcare platform.
    • Affordable diagnostic solutions with timely and accurate test results.
    • Up to 60% discount on Doorstep Diagnostic Tests, Home Sample Collection.
    • An inventory of over 100+ laboratories, spread across the country, operating out of 120+ cities with 1200+ collection centers, serving over 1800+ pin codes.

    The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results