apollo

Nk Cell Panel - CD3, CD16 / CD56

No preparation required

MRP706725% off
5300
circle logo₹265 cashback

testsTest(s) Included (5)

  • Nk Cell Panel - CD3, CD16 / CD56

    5 tests included

    expand

About

blood sample
Sample

BLOOD

Gender
Gender

Both

users
Age group

7 years & above

Natural killer (NK) cells are a part of your immune system that kills foreign pathogenic invaders and neutralises their harmful reactions. Every organ has plenty of NK cells, including the reproductive organs. The natural killer cells in the uterus play an important role when a woman is pregnant.

During the plantation of the embryo to the uterine wall, these cells cause inflammation to assist in proper attachment. However, excess or lack of NK cells can cause infertility or a miscarriage during pregnancy.

A natural killer cell test is suitable for identifying chronic infections like HIV-1 and hepatitis C virus. In this test, the surface molecules known as cluster of differentiation (CD) play a primary role in determining the immune response. These molecules are responsible for cell-cell communication during the immune reaction.

Since there are several CD molecules, each is considered a marker for a particular health condition. CD3, CD16 and CD56 are the markers for inflammation and tumour response, respectively.

As per multiple studies, the average percentage of CD16/CD56 NK cells in the body varies from 5% to 29%. Hence, if the NK cell panel test reflects more than 12% of CD cells, it indicates miscarriage or infertility in women. Similarly, the NK cell test shows a range between 2% and 38% during chronic infections.

Apollo 24|7 has an explicit panel for the NK cell test that is taken under the following circumstances:

  • To identify or monitor the progress of an HIV infection
  • To observe the problems related to immune deficiency with NK cell defect
  • NK cell lymphocytosis 
  • Before or after solid organ transplantation 
  • To assess the reconstitution of the immune system after bone marrow transplantation or hematopoietic cell transplantation

Natural killer cells are not a homogenous set of molecules. The most common combination of surface markers includes CD3, CD16, and CD56. These molecules are responsible for producing the following types of reactions in the body:

  • CD3: It is a T-cell receptor that has a significant role in activating T-cell-mediated immune response. It transduces the signal after recognising the antigens and activates T-lymphocytes. 
  • CD16: This is an Fc receptor that facilitates antibody-dependent cellular cytotoxicity by binding to several antibodies. It is mainly responsible for tumour surveillance and low affinity toward IgG. 
  • CD56: This neural cell adhesion molecule indicates inflammation in particular sites. These are homing markers for the inflammation, i.e., they rush immediately to the site of inflammation and are easier to test. 

NK cell test identifies ongoing viral infection and its effects due to a lack of sufficient natural killer cells. 

faqFrequently Asked Questions (FAQs)

How are NK cells test helpful in identifying a women’s reproductive health?

Natural killer cell test identifies the increasing or decreasing levels of NK cells in a women’s body. The concentration is high during menstruation and crosses the optimum amount during the implantation phase of pregnancy. Sometimes, when the amount of NK cells is exceptionally high, the immune system identifies the foetus as a foreign substance and starts attacking it. This leads to miscarriages and unsuccessful conception despite proper fertilisation. NK cell test panel identifies these fluctuations and makes them easier to manage.

Is any special preparation required for the natural killer cell test?

The test does not require special preparations because it involves a simple blood examination. The phlebotomist draws a minimum of 2 ml of blood from the vein in a dedicated test tube to avoid blood clotting. The service provider needs to clean the area before and after drawing the blood to prevent any infection on the surface.

What does the NK cells test indicate?

Natural killer cell test indicates your body’s immune reaction level. It could be high or low, depending on your infection. Moreover, to improve your condition, you might need an intervention of immune therapy. The medication usually involves a certain kind of immunosuppressive drug that might reduce the level of NK cells and inflammation.

Does a high level of natural killer cells in the NK cell test mean permanent infertility?

No. The test results are just an assessment to start medication. A few miscarriages or failed conceptions do not imply permanent infertility.

What is the role of CD16 in HIV infection?

CD16 is an important biomarker of HIV-1 infection. These express higher levels of CCR5. Hence, higher levels of CD16 indicate the presence of chronic viral disease and allow the physicians to start the treatment.

Why does the NK cell level affect a woman's reproductive health?

The abnormal levels of NK cells in the natural killer cell test indicate the presence of an autoimmune disease that causes recurrent miscarriages. The treatment usually involves medication such as prednisone or intravenous immunoglobulin.

Most Popular tests & packages

Complete Blood Count (CBC) | Glucose, Fasting | HbA1c, Glycated Hemoglobin | Dengue NS1 Antigen - Elisa | Complete Urine Examination | Glucose, Post Prandial (PP), 2 Hours (Post Meal) | Lipid Profile | Liver Function Test (LFT) | Thyroid Profile (Total T3, Total T4, TSH) | Thyroid Stimulating Hormone (TSH), Serum | C - Reactive Protein CRP (Quantitative) | Creatinine, Serum | Platelet Count | Culture And Sensitivity Urine | Peripheral Smear For Malarial Parasite (MP) | Renal Profile/Renal Function Test (RFT/KFT) | Widal Test ( Slide Method ) | Glucose, Random | Dengue Profile - Elisa | Uric Acid - Serum | Erythrocyte Sedimentation Rate (ESR) | Total Beta - HCG (TB-HCG) | Hemoglobin | Hemogram | Electrolytes - Serum | Vitamin B12 | Prothrombin Time (PT/INR) | Potassium - Serum / Plasma | Thyroid Profile - Free (FT3, FT4, TSH) | Urea And Creatinine | Sodium - Serum | Vitamin D - 25 Hydroxy (D2+D3) | Blood Group ABO And RH Factor | Dengue Fever NS1 Antigen, Rapid | Hiv Rapid

Nk Cell Panel - CD3, CD16 / CD56 near you

Nk Cell Panel - CD3, CD16 / CD56 in Beeramguda | Nk Cell Panel - CD3, CD16 / CD56 in Begumpet | Nk Cell Panel - CD3, CD16 / CD56 in Kondapur Junction | Nk Cell Panel - CD3, CD16 / CD56 in Kondapur | Nk Cell Panel - CD3, CD16 / CD56 in Kukatpally Housing Board Colony | Nk Cell Panel - CD3, CD16 / CD56 in Kukatpally Metro Parking | Nk Cell Panel - CD3, CD16 / CD56 in Lingampally | Nk Cell Panel - CD3, CD16 / CD56 in Madhapur | Nk Cell Panel - CD3, CD16 / CD56 in Manikonda | Nk Cell Panel - CD3, CD16 / CD56 in Miyapur | Nk Cell Panel - CD3, CD16 / CD56 in My Home Jewel Road | Nk Cell Panel - CD3, CD16 / CD56 in Nizampet | Nk Cell Panel - CD3, CD16 / CD56 in Sri Lakshmi Residency | Nk Cell Panel - CD3, CD16 / CD56 in Malkajgiri | Nk Cell Panel - CD3, CD16 / CD56 in Gachibowli | Nk Cell Panel - CD3, CD16 / CD56 in Gopanapalli | Nk Cell Panel - CD3, CD16 / CD56 in Jagadgiri Gutta | Nk Cell Panel - CD3, CD16 / CD56 in Kanaka Durga Temple | Nk Cell Panel - CD3, CD16 / CD56 in Masjid Banda | Nk Cell Panel - CD3, CD16 / CD56 in Mayuri Nagar Welfare Association | Nk Cell Panel - CD3, CD16 / CD56 in Palm Breeze Rd | Nk Cell Panel - CD3, CD16 / CD56 in Pragathi Enclave | Nk Cell Panel - CD3, CD16 / CD56 in Rtc Colony | Nk Cell Panel - CD3, CD16 / CD56 in Kothaguda X Road | Nk Cell Panel - CD3, CD16 / CD56 in Rethibowli | Nk Cell Panel - CD3, CD16 / CD56 in Banjara Hills | Nk Cell Panel - CD3, CD16 / CD56 in Borabanda | Nk Cell Panel - CD3, CD16 / CD56 in Kukatpally | Nk Cell Panel - CD3, CD16 / CD56 in Hitech City | Nk Cell Panel - CD3, CD16 / CD56 in Bhaskar Nagar | Nk Cell Panel - CD3, CD16 / CD56 in Manikonda | Nk Cell Panel - CD3, CD16 / CD56 in Balanagar Township | Nk Cell Panel - CD3, CD16 / CD56 in Hmt Township | Nk Cell Panel - CD3, CD16 / CD56 in Nizampet | Nk Cell Panel - CD3, CD16 / CD56 in Administrative Buildings | Nk Cell Panel - CD3, CD16 / CD56 in Amberpet | Nk Cell Panel - CD3, CD16 / CD56 in Attapur | Nk Cell Panel - CD3, CD16 / CD56 in Central Secretariat | Nk Cell Panel - CD3, CD16 / CD56 in Dattatreya Colony | Nk Cell Panel - CD3, CD16 / CD56 in Falaknuma | Nk Cell Panel - CD3, CD16 / CD56 in Hasannagar | Nk Cell Panel - CD3, CD16 / CD56 in I.e.nacharam | Nk Cell Panel - CD3, CD16 / CD56 in Jubilee Hills | Nk Cell Panel - CD3, CD16 / CD56 in Malakpet Colony | Nk Cell Panel - CD3, CD16 / CD56 in Raj Bhawan | Nk Cell Panel - CD3, CD16 / CD56 in Sitaphalmandi | Nk Cell Panel - CD3, CD16 / CD56 in Cuc | Nk Cell Panel - CD3, CD16 / CD56 in Manuu | Nk Cell Panel - CD3, CD16 / CD56 in Bowenpally

Why should Apollo be your preferred healthcare partner?

  • 40 Years of legacy and credibility in the healthcare industry.
  • NABL certified multi-channel digital healthcare platform.
  • Affordable diagnostic solutions with timely and accurate test results.
  • Up to 60% discount on Doorstep Diagnostic Tests, Home Sample Collection.
  • An inventory of over 100+ laboratories, spread across the country, operating out of 120+ cities with 1200+ collection centers, serving over 1800+ pin codes.

The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results