apollo
Search

Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01)

No preparation required

MRP1013325% off
7600
circle logo₹532 cashback

testsTest(s) Included (1)

  • HLA CELIAC DISEASE (DQB1*02, 1*03, DQA1*05;01)

About

blood sample
Sample

BLOOD

Gender
Gender

Both

users
Age group

7 years & above

Celiac disease is an autoimmune disorder that is associated with gluten consumption. It causes swelling and damage to the small intestine (enteropathy) triggered by the gluten in your staple diet, including wheat, rye, barley, and other similar grains. Gluten is the substance that gives bread and dough a chewy texture.

Being an autoimmune disease, a genetic test for celiac disease helps identify the severity of the condition. It is also easier for the physician to do disease typing based on the antigen present in the body.

The disease involves a reaction to villi or finger-like projections inside the gut. This reduces the nutrition quotient of a gluten-based diet and prevents absorption of other substances. Ultimately, the disease causes malnourishment in the affected person.

The HLA DQ test for celiac disease is a necessary biomarker test since this condition combines genetic and non-genetic factors. Nearly 30% of the population code for HLA class II antigens that involve HLA DQ2 and DQ8 genes. These genes are expressed strongly when a person has celiac disease.

Out of 30% of people coding for the gene, only 1% develop the condition. Hence, a test is essential for people who might be prone to celiac disease due to inherited genes. Here is a list of people who must get a genetic test for celiac disease:

  • People with a family history of celiac disease.
  • Individuals who observe intestinal inflammation immediately after consuming a gluten-based diet.
  • People with digestive symptoms that are not associated with infection and other disorders.

Apollo 24|7 has an all-inclusive celiac disease test that helps detect the presence of HLA DQ genes in the blood.

HLA stands for human leukocyte antigen found in the major histocompatibility complex. The antigens for celiac disease are in the class II region known as HLA-DQA1 and HLA-DQB1. The HLA-DQ molecules are present on the surface of antigen-presenting cells. These are the surface proteins that HLA DQ tests for celiac disease analyses.

The celiac disease test also determines the alleles or proteins present in the patient. The genetic test for celiac disease usually differentiates between DQA1 and DQB1.

Following are the components that determine the severity of the disease:

  • HLA-DQ2.5: Nearly 90% of the patients have the disease code for this DQ2 molecule.
  • HLA-DQ8: This is not a very significant marker of the disease as only 20% of the patients have this protein. 
  • HLA-DQ2.2: It is considered a supportive marker for the disease since it is not present in most patients. This heterodimer is present only in 35% of the patients.
  • HLA DQ test for celiac disease not only confirms the condition but also rules out the possibility of the disease.
     

Medically reviewed by Dr. P Siva Charan Reddy, Surgical gastroenterologist, Apollo Hospitals Jubilee Hills, Hyderabad.

faqFrequently Asked Questions (FAQs)

Frequently asked questions

Before the confirmation of the condition, you might observe the following symptoms of the disease in your body: Frequent abdominal pain after a few minutes of eating food Common symptoms like bloating, heartburn, mouth ulcers, diarrhoea, constipation, and nausea  Presence of flatulence  Faeces with a distinct smell and a pale colour
Anaemia is not a symptom of celiac disease but a consequence. Since the absorption of nutrients is hampered due to autoimmune reactions in the body, the affected individual cannot receive proper nourishment. This leads to anaemia and other symptoms like bone and joint pain.
When other serologic tests and immune system assessments cannot yield good results, the HLA DQ test for celiac disease helps confirm or rule out the condition.
Yes. It is very much possible for a child to develop this condition. They also have similar symptoms in their digestive system that indicate the disease’s presence. However, the symptoms in children also include unexplained weight loss, swelling in the belly, and vomiting.
Children must opt for a genetic test for celiac disease as soon as they notice unusual digestive ailments without any infection. This is because the development of celiac disease at an early age could have long-term damaging effects like learning disabilities, delayed puberty, slow growth, and short height. Additionally, the kids may develop ADHD and other neurological disorders. Many infants are unable to survive for a long time and those who do have unruly behaviour and frequent mood swings.
Yes. This is an important test that indicates if you are the gene carrier. It further helps in taking necessary steps for your progeny, if at all you happen to be carrying the gene.

Most Popular tests & packages

Complete Blood Count (CBC) | Glucose, Fasting | HbA1c, Glycated Hemoglobin | Dengue NS1 Antigen - Elisa | Complete Urine Examination | Glucose, Post Prandial (PP), 2 Hours (Post Meal) | Lipid Profile | Liver Function Test (LFT) | Thyroid Profile (Total T3, Total T4, TSH) | Thyroid Stimulating Hormone (TSH), Serum | C - Reactive Protein CRP (Quantitative) | Creatinine, Serum | Platelet Count | Culture And Sensitivity Urine | Peripheral Smear For Malarial Parasite (MP) | Renal Profile/Renal Function Test (RFT/KFT) | Widal Test ( Slide Method ) | Glucose, Random | Dengue Profile - Elisa | Uric Acid - Serum | Erythrocyte Sedimentation Rate (ESR) | Total Beta - HCG (TB-HCG) | Hemoglobin | Hemogram | Electrolytes - Serum | Vitamin B12 | Prothrombin Time (PT/INR) | Potassium - Serum / Plasma | Thyroid Profile - Free (FT3, FT4, TSH) | Urea And Creatinine | Sodium - Serum | Vitamin D - 25 Hydroxy (D2+D3) | Blood Group ABO And RH Factor | Dengue Fever NS1 Antigen, Rapid | Hiv Rapid

Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) near you

Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Beeramguda | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Begumpet | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Kondapur Junction | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Kondapur | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Kukatpally Housing Board Colony | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Kukatpally Metro Parking | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Lingampally | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Madhapur | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Manikonda | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Miyapur | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in My Home Jewel Road | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Nizampet | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Sri Lakshmi Residency | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Malkajgiri | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Gachibowli | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Gopanapalli | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Jagadgiri Gutta | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Kanaka Durga Temple | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Masjid Banda | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Mayuri Nagar Welfare Association | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Palm Breeze Rd | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Pragathi Enclave | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Rtc Colony | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Kothaguda X Road | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Rethibowli | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Banjara Hills | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Borabanda | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Kukatpally | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Hitech City | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Bhaskar Nagar | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Manikonda | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Balanagar Township | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Hmt Township | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Nizampet | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Administrative Buildings | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Amberpet | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Attapur | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Central Secretariat | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Dattatreya Colony | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Falaknuma | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Hasannagar | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in I.e.nacharam | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Jubilee Hills | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Malakpet Colony | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Raj Bhawan | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Sitaphalmandi | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Cuc | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Manuu | Hla Celiac Disease (Dqb1*02, 1*03, Dqa1*05;01) in Bowenpally

Why should Apollo be your preferred healthcare partner?

  • 40 Years of legacy and credibility in the healthcare industry.
  • NABL certified multi-channel digital healthcare platform.
  • Affordable diagnostic solutions with timely and accurate test results.
  • Up to 60% discount on Doorstep Diagnostic Tests, Home Sample Collection.
  • An inventory of over 100+ laboratories, spread across the country, operating out of 120+ cities with 1200+ collection centers, serving over 1800+ pin codes.

The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results