IgF- Bp3 ( Insulin Growth Factor - Binding Protein 3) in Adyar, Chennai

IGF-BP3 (Insulin-like Growth Factor-Binding Protein 3) Test: Price, Purpose, Range & Reports
 

The IGF-BP3 (Insulin-like Growth Factor-Binding Protein 3) test is a key blood test used to evaluate the function of the Growth Hormone (GH) axis. IGF-BP3 is the primary carrier protein for Insulin-like Growth Factor-I (IGF-I) in the bloodstream. Since circulating GH levels fluctuate widely throughout the day, measuring GH directly can be unreliable. Therefore, IGF-BP3, whose levels are stable and directly dependent on GH secretion, serves as a superior and more practical indicator of average GH status. The test is critical in diagnosing disorders related to growth hormone excess (like acromegaly or gigantism) and growth hormone deficiency. 
If you are looking for the IGF-BP3 Test price or need to schedule this endocrine function assessment, you can search for the service through Apollo 24|7 to find accredited lab testing options near you.

What is the IGF-BP3 (Insulin-like Growth Factor-Binding Protein 3) Test?

The IGF-BP3 Test is a blood test that measures the concentration of Insulin-like Growth Factor-Binding Protein 3. This protein plays a vital role in the body by binding to and regulating IGF-I, which is produced by the liver in response to Growth Hormone. IGF-BP3 carries about 75 % to 90 % of circulating IGF-I, dramatically extending its half-life and stabilising its concentration in the blood. By measuring IGF-BP3, clinicians gain a stable, integrated measure of Growth Hormone activity over time, providing a clear picture of whether the pituitary gland is producing normal amounts of GH.

What is the IGF-BP3 Test Price?

The price of the IGF-BP3 Test reflects the specialised nature of the assay, the complexity of its interpretation in the context of growth and endocrine health, and the requirement for specific reference ranges based on age and pubertal status. Several factors influence the final cost of the test:

•    Assay Complexity: The test involves specialised immunoassay techniques to accurately measure the binding protein, which can be more expensive than general chemistry panels.
•    Location: Pricing may vary between cities due to differences in operational costs, logistics, and regional healthcare infrastructure.
•    Service Type: The test is typically performed on a blood sample collected at a lab or collection centre.
•    Lab Accreditation: For reliable results, especially in diagnosing chronic conditions, testing should be performed at accredited laboratories (such as those approved by NABL), ensuring the highest standards of quality control and analytical accuracy.
If you're looking for the most accurate and affordable IGF-BP3 Test price near you, the best way to check is through the Apollo 24|7 website or app. Prices are updated regularly based on your location, and you’ll be able to view the latest rates along with any available discounts or offers.

What is the Purpose of the IGF-BP3 Test?

The primary purpose of the IGF-BP3 Test is to assess the overall function of the Growth Hormone/IGF-I axis. Key applications include:

•    Diagnosis of Growth Hormone Deficiency (GHD): Along with IGF-I, low levels of IGF-BP3 can strongly suggest GHD in both children (who present with poor growth) and adults (who may present with metabolic symptoms).
•    Diagnosis of Growth Hormone Excess: Elevated levels of IGF-BP3 (and IGF-I) are used to confirm the diagnosis of Acromegaly in adults or Gigantism in children, conditions typically caused by a pituitary tumour.
•    Monitoring Treatment: Used to monitor the effectiveness and safety of Growth Hormone replacement therapy in GHD patients, or to assess the efficacy of treatment aimed at lowering GH in acromegaly patients.
•    Nutritional Status Assessment: Since IGF-BP3 production is also dependent on adequate nutrition, the test can sometimes serve as an indicator of severe malnutrition or chronic liver disease, which impairs the liver's ability to synthesise the protein.

Who Should Get an IGF-BP3 Test Done?

An IGF-BP3 (Insulin-like Growth Factor-Binding Protein 3) test is typically recommended when a healthcare provider suspects an issue with growth hormone production or regulation. This test helps assess how well the body is responding to growth hormone and is often used alongside IGF-1 testing for a more complete evaluation.

You may be advised to take this test if:

•    A child shows signs of stunted growth or delayed development, which could indicate a growth hormone deficiency.
•    An adult has symptoms of growth hormone deficiency, such as fatigue, reduced muscle mass, or changes in body composition, especially if they had growth issues in childhood.
•    There are signs of excessive growth hormone, such as enlarged hands, feet, or facial features, which may suggest conditions like acromegaly or gigantism.
•    You are undergoing growth hormone therapy, and your doctor needs to monitor how your body is responding to treatment.
•    There is concern about malnutrition or liver dysfunction, as IGF-BP3 levels can also reflect nutritional status and liver health in certain clinical situations.
This test provides valuable insight into growth-related conditions and helps guide diagnosis and treatment decisions.

Components of the IGF-BP3 Test

•    IGF-BP3 (Insulin-like Growth Factor-Binding Protein 3)

This panel includes a single test that measures the level of IGF-BP3 in the blood. IGF-BP3 is the primary binding protein for insulin-like growth factors and plays a key role in regulating their activity. It is commonly used to assess growth hormone function and is often ordered alongside IGF-1 for a more accurate evaluation of growth-related disorders.

Understanding an IGF-BP3 Test Report

The interpretation of an IGF-BP3 result is highly dependent on the patient's age, and in children, their pubertal stage (Tanner stage), as IGF-BP3 levels naturally peak during puberty.

 A single reference range is not appropriate for all patients.

Typical Reference Ranges

Note: Reference ranges vary significantly between laboratories based on the assay used. Always use the range provided on your specific lab report.
 

Interpreting Your Results

•    Low IGF-BP3: May indicate growth hormone deficiency or insensitivity. It can also be associated with malnutrition, severe liver disease, or hypothyroidism.
•    High IGF-BP3: May suggest excess growth hormone, as seen in conditions like acromegaly or gigantism. Elevated levels are also expected during normal puberty.
•    Normal IGF-BP3: Within the appropriate age range, a normal result generally rules out major growth hormone axis disorders. However, further testing may be needed if symptoms persist or clinical suspicion remains high.
Your healthcare provider will interpret your IGF-BP3 result in the context of your age, symptoms, and other hormone levels, often alongside IGF-1 testing, to guide diagnosis and treatment decisions.

Preparation and Procedure for IGF-BP3 Test

The procedure for this test is simple, requiring only a blood draw.

1. How is the Test Done?

A healthcare professional will draw a standard blood sample from a vein in your arm (venipuncture). The blood is collected into a special tube, often containing a serum separator gel to help isolate the serum for testing. Once collected, the sample is sent to a laboratory where it is analysed to measure the level of IGF-BP3 in your bloodstream. 

2. Is Fasting Required for This Test?

Fasting is generally NOT required for the IGF-BP3 test, as its levels are stable and not influenced by recent food intake. However, always follow the specific instructions provided by your ordering physician or lab.

3. What Time of the Day Should I Undergo the Test?

No specific timing is required. Since IGF-BP3 levels are relatively stable throughout the day (unlike the highly variable Growth Hormone), the sample can be collected at any time.

4. Should I Inform My Doctor About Other Medications I Am Taking?

Yes. Always inform your doctor about all medications you are taking, including prescribed hormones, supplements, or steroids, as these can potentially influence endocrine axis tests.

Booking IGF-BP3 Test Online & Checking Reports

Apollo 24|7 offers a seamless process for scheduling this important test and accessing your results.

A. How to Schedule the Test on Apollo 24|7

•    Visit the Apollo 24|7 platform and search for IGF-BP3 Test or Insulin-like Growth Factor-Binding Protein 3.
•    Review the latest IGF-BP3 Test price for your location and click 'Book Now'.
•    Select a convenient date and time for the sample collection at the designated facility/lab centre.
•    Complete the secure online payment to confirm your booking.

B. How to Access Your Test Results Online

•    Log in to your Apollo 24|7 account via the website or mobile app.
•    Navigate to the 'Health Records' or 'My Reports' section.
•    Click on the completed IGF-BP3 Test report.
•    You can view and download the detailed report in PDF format, which should be shared with your endocrinologist or primary care physician for interpretation.

Conclusion

The IGF-BP3 test is a simple but important way to check how your body is using growth hormone. Because IGF-BP3 levels stay fairly steady and are closely linked to growth hormone activity, this test is especially helpful for spotting growth problems in children and hormone-related conditions in adults. It gives doctors useful information to help diagnose issues and track how well treatments are working.