Effective price: ₹2371
Above 10 years
Organ transplant is an extensive process which requires the replacement of a diseased organ with a healthy one. During the allograft or transplant procedure, the receiving body must have a strong immunity to withstand the internal organ accommodation.
A majority of organ transplants fail because the receiver's body doesn't acknowledge the transferred tissue as its own. It happens because the immune system gets triggered after the transplantation, which releases antibodies causing the whole surgery to fail. Besides, antibody-mediated rejection (AMR) also interferes with post-surgery drug treatment.
Organ rejection does not happen immediately. Typically, there are two types of rejection after an allograft:
Transplant rejection causes a variety of symptoms in the body, slowly leading to permanent organ damage. These signs include:
To avoid such post-allograft symptoms and control the organ damage, the C4D IHC marker is commonly considered by surgeons. This biomarker acts as an indicator of the receiving body's tolerance for antibody-mediated rejection and graft survival. C4D marker is commonly known as a 'magic marker' due to its ability to detect any tissue injury in the transplanted organ inflicted by the antibodies.
The C4D test is conducted using a tissue sample from the transplanted area to detect the sensitivity for any potential AMR dysfunction. Thereafter, the acquired sample is preserved in a paraffin block. The lab technician ensures that no sample corruption occurs either through heat exposure or foreign pollutant for accurate immunohistochemistry C4D test results.
Based on the C4D IHC deposition in the sample, the sensitivity is specified. The higher the C4D fragment presence, the stronger is the intensity of antibody-mediated rejection.
Side-effects of C4D marker specimen collection are rare, however, you can look out for:
Most of the side effects last for a few days only. However, if the issue persists, contact a certified medical practitioner.
Apollo 24|7 offers immunohistochemistry individual marker C4D test by incorporating adequate safety and collection mechanisms. The major benefits of opting for the C4D fragment test include:
Why should Apollo be your preferred healthcare partner?
The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results