Double Marker Test In Chennai

Overview of the Double Marker Test

Test Overview

The Double Marker Test is a first-trimester prenatal screening performed between 9 and 13 weeks of pregnancy to assess the risk of chromosomal abnormalities, particularly Down syndrome (Trisomy 21) and Edwards syndrome (Trisomy 18). It measures two key biomarkers in the mother's blood: free Beta-human Chorionic Gonadotropin (β-hCG) and Pregnancy-Associated Plasma Protein-A (PAPP-A). Abnormal levels of these markers may indicate an increased risk of genetic disorders, prompting further evaluation.

While the Double Marker Test does not provide a definitive diagnosis, it serves as an important screening tool to identify pregnancies that may need additional testing. If results suggest a higher risk, Non-Invasive Prenatal Testing (NIPT), amniocentesis, or chorionic villus sampling (CVS) may be recommended for confirmation. To enhance accuracy, the test is often performed alongside nuchal translucency (NT) ultrasound. It is particularly advised for women over 35, those with a family history of genetic disorders, or individuals with high-risk pregnancy factors.

Tests Included in Double Marker Test in Chennai

The double marker test in pregnancy, also known as the dual marker test or dual test in pregnancy, involves analyzing two key components in the mother's blood.

• Pregnancy-Associated Plasma Protein A (PAPP-A): PAPP-A is a protein secreted by the placenta during pregnancy. Lower-than-normal levels of this protein may indicate a higher risk of chromosomal abnormalities, such as Down syndrome or Edward's syndrome.
• Free Beta-Human Chorionic Gonadotropin (β-hCG): β-hCG is a hormone produced by the placenta that plays a crucial role in sustaining pregnancy. Elevated levels of β-hCG can be associated with an increased risk of conditions like Down syndrome.

By combining the results of these two markers with factors such as the mother's age, gestational age, and nuchal translucency measurements, the dual marker test calculates a risk score. This risk assessment helps identify pregnancies that may benefit from further diagnostic tests, such as amniocentesis or chorionic villus sampling.

What Medical Treatments/Procedures Can Require the Double Marker Test?

The Double Marker Test is recommended as part of routine prenatal screening and may be required in specific medical treatments or procedures, including:

• High-Risk Pregnancy Management – Women over 35, those with a history of genetic disorders, or previous pregnancy complications may need this test for risk assessment.
• In-Vitro Fertilization (IVF) Pregnancies – Since IVF pregnancies can have a slightly higher risk of chromosomal abnormalities, doctors often recommend this test for early screening.
• Nuchal Translucency (NT) Screening Follow-Up – If an NT ultrasound suggests an increased risk of chromosomal abnormalities, the Double Marker Test may be advised for further evaluation.
• Genetic Counseling & Risk Assessment – Couples with a family history of genetic conditions may require this test as part of their prenatal care.
• Planned Diagnostic Testing – If parents are considering Non-Invasive Prenatal Testing (NIPT), amniocentesis, or chorionic villus sampling (CVS), the Double Marker Test results may help determine the need for further procedures.

This test aids in early risk identification, allowing parents and healthcare providers to make informed decisions about further diagnostic testing or pregnancy management.

Test Requirements

The Double Marker Test is a simple blood test that requires minimal preparation. Below are the key requirements:

• Timing: It is typically performed between 9 to 13 weeks of pregnancy, often in conjunction with a nuchal translucency (NT) ultrasound.
• Fasting: Generally, fasting is not required, but some healthcare providers may advise it based on individual cases.
• Sample Collection: A blood sample is drawn from the mother's arm for analysis.
• Medical History: Inform your doctor about any pre-existing health conditions, medications, or previous pregnancy complications, as these factors may influence the interpretation of results.
• Doctor’s Recommendation: The test is usually recommended for women over 35 years of age, those with a family history of genetic disorders, or individuals with high-risk pregnancy factors.

The results of the Double Marker Test are analyzed alongside ultrasound findings to provide a more accurate risk assessment for chromosomal abnormalities. If the results indicate an increased risk, additional diagnostic tests such as Non-Invasive Prenatal Testing (NIPT), amniocentesis, or chorionic villus sampling (CVS) may be recommended.

Price of the Double Marker Test in Chennai

Double Marker Test  Price in Different Cities

The cost of the Double Marker Test varies depending on factors such as the location, diagnostic centre, healthcare provider, and additional services offered.

• Location: Diagnostic centres in metropolitan cities or private hospitals might charge more than smaller clinics in rural or less densely populated areas.
• Package Deals: Many diagnostic centres offer bundled packages that include the Double Marker Test alongside other prenatal tests (e.g., Quadruple Marker Test, Nuchal Translucency Scan, etc.), which could influence the overall cost. These packages may offer a discounted rate when tests are purchased together.
• Type of Test: Some labs may offer advanced versions of the Double Marker Test that include extra features or higher accuracy, which may lead to a slightly higher price.

To get the most accurate and updated details about the double marker test price, it’s a good idea to check with local clinics or trusted online medical services. Many platforms, like Apollo 24|7, make it easy to book the test and also share pricing details upfront, so you know what to expect.

Reports of the Double Marker Test

The Double Marker Test provides risk scores based on your blood levels and other factors, such as maternal age. These scores are usually presented as ratios, like 1 in 1000 or 1 in 50. Here’s how to interpret these results:

Important Note:

• The Double Marker Test is a screening test, not a diagnostic test.
• Always discuss the results with your doctor to understand the next steps.

How Often Should You Be Recommended Double Marker Test?

The Double Marker Test is a one-time prenatal screening test typically performed between 9 and 13 weeks of pregnancy. It is not repeated unless specific concerns arise, such as:

• Abnormal First-Trimester Screening Results – If earlier screenings suggest a potential risk of chromosomal abnormalities, doctors may recommend additional tests.
• Unclear or Borderline Results – In cases where initial results are inconclusive, a repeat test or further diagnostic procedures like Non-Invasive Prenatal Testing (NIPT), amniocentesis, or chorionic villus sampling (CVS) may be advised.
• High-Risk Pregnancies – If a woman has a higher risk due to age, genetic predisposition, or other medical factors, further evaluation beyond the Double Marker Test may be necessary.

Since this test is a screening tool rather than a diagnostic test, it is generally conducted only once during pregnancy unless further assessments are required based on the results.

Book the Double Marker Test Online

Booking a Double Marker Test through Apollo 24|7 is quick and can be done from the comfort of your home. Here’s how:1.1.

1.Visit the Apollo 24|7 Website or App

Start by visiting the official Apollo 24|7 website or download the easy-to-use Apollo 24|7 mobile app from the App Store or Google Play. The platform is designed to be user-friendly and straightforward for seamless navigation.

2.Search for the Test

On the homepage, you’ll find a search bar at the top of the page. Type in "Double Marker Test" to find the dedicated test page for screening for conditions like Down syndrome (Trisomy 21) and Trisomy 18.

3.Select a Convenient Time and Location

Once you’re on the Double Marker Test page, choose a time slot that works best for you. You can also select your preferred location from the available collection centres or diagnostic facilities. The page will also provide information on the cost of the test.

4.Complete the Booking

After selecting your time and location, fill in the required details to complete the booking process. Ensure all information is accurate to avoid any issues during the test.

5.Receive Booking Confirmation

After completing your booking, you’ll receive a confirmation message or email from Apollo 24|7 with your appointment details. This confirms that your test request has been successfully processed.