MATERNAL SERUM SCREENING - DOUBLE MARKER WITH PLGF in Guru-tegh-bahadur-nagar-west, Mumbai

MATERNAL SERUM SCREENING – DOUBLE MARKER WITH PLGF Test: Price, Purpose, Range & Report Interpretation

Test Overview

Prenatal screening plays a vital role in assessing the health of both the mother and the developing baby. The Maternal Serum Screening – Double Marker with PLGF Test is an advanced blood test designed to evaluate the risk of chromosomal abnormalities in the foetus, such as Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and Patau syndrome (Trisomy 13). This test measures two essential biochemical markers, Free Beta hCG (human chorionic gonadotropin) and PAPP-A (Pregnancy-Associated Plasma Protein-A), along with PLGF (Placental Growth Factor), which provides additional insights into placental health and pregnancy risks like preeclampsia. If you are searching for a Double Marker with PLGF Test near me, Apollo 24|7 offers home sample collection, NABL-accredited testing, and digital report access for expectant mothers across India. This guide explains the Double Marker with PLGF Test price, purpose, procedure, interpretation, and booking details.

What is the Maternal Serum Screening – Double Marker with PLGF Test?

The Double Marker with PLGF Test is a specialised prenatal blood screening test that assesses the risk of certain chromosomal abnormalities in the developing foetus. It combines maternal blood biochemistry with ultrasound data (nuchal translucency measurement) to calculate a personalised risk score.

• Double Marker Test: Measures Free Beta hCG and PAPP-A, key hormones produced during pregnancy. Abnormal levels may indicate an increased risk of chromosomal anomalies.
• PLGF (Placental Growth Factor): A placental protein that supports blood vessel formation. Low levels of PLGF are linked to complications such as preeclampsia, intrauterine growth restriction (IUGR), and other placental disorders.
• By integrating PLGF with the standard double marker profile, the test enhances accuracy for predicting not only chromosomal risks but also placental health and maternal complications.

Why is the Double Marker with PLGF Test Recommended?

Doctors recommend this test as part of first-trimester screening (between 10 to 13 weeks of pregnancy) to identify high-risk pregnancies early. It is especially useful when:

The expectant mother is over 30 years of age, as chromosomal risks increase with maternal age.

• There is a family history of chromosomal disorders.
• The first-trimester ultrasound indicates increased nuchal translucency (NT).
• The mother has gestational risk factors like high blood pressure, diabetes, or prior pregnancy complications.
• The clinician wants a more comprehensive evaluation of placental function to predict early-onset preeclampsia.

This test helps in early counselling, further diagnostic testing (if needed), and proactive management for a healthy pregnancy outcome.

What is the Double Marker with PLGF Test Price?

The Double Marker with PLGF Test price varies depending on several factors:

• Location: Test prices may differ between cities (e.g., Mumbai vs. Chennai).
• Service Type: Home sample collection may add a small convenience fee.
• Laboratory Accreditation: NABL-accredited centres ensure high accuracy and reliability.
• Package Offers: Apollo 24|7 often provides bundled discounts on pregnancy screening packages.
• For the most accurate and updated pricing in your area, visit the Apollo 24|7 website or app before booking your test.

Purpose of the Double Marker with PLGF Test

The primary purpose of this test is to assess the foetal risk of chromosomal abnormalities and evaluate placental health. Doctors recommend it to:

• Screening for Chromosomal Abnormalities: It helps identify the risk of conditions such as Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and Patau syndrome (Trisomy 13), allowing for early detection and appropriate planning.
• Evaluating Placental Function and Maternal Health: The test measures Placental Growth Factor (PlGF) to assess placental development, helping to identify potential risks for maternal complications like preeclampsia or foetal growth restrictions such as intrauterine growth restriction (IUGR).
• Guiding Further Diagnostic Testing: Based on the results, doctors can determine the need for confirmatory procedures such as Non-Invasive Prenatal Testing (NIPT), Chorionic Villus Sampling (CVS), or amniocentesis to confirm chromosomal abnormalities.
• Providing Reassurance and Timely Management: For low-risk pregnancies, the test provides reassurance to expectant parents. In high-risk cases, it enables early interventions and closer monitoring to ensure both maternal and foetal well-being.

Who Should Get the Test Done?

Your doctor may recommend the Double Marker with PLGF Test if:

• You are in your first trimester (10 to 13 weeks).
• You are above 30 years of age or have a family history of chromosomal abnormalities.
• You had a previous pregnancy affected by genetic disorders or preeclampsia.
• You experience abnormal ultrasound findings (e.g., increased nuchal translucency).
• You want a non-invasive screening option before considering invasive tests.

What Does the Test Measure?

The Double Marker with PLGF Test measures the following parameters:

Understanding the Double Marker with PLGF Test Report

The report provides a risk ratio (e.g., 1 in 5000 or 1 in 200) comparing your results to baseline risk levels. It also includes comments on placental function and foetal health indicators.

Preparation and Procedure for the Test

To ensure accurate and reliable results, it’s important to follow certain preparation guidelines and understand how the Double Marker with PLGF test is performed. Here’s what you need to know before your sample collection and testing procedure.

Preparation:

• No fasting is required.
• Inform your doctor of any medications or supplements you are taking.
• Provide accurate gestational age and ultrasound NT measurement for best interpretation.

Procedure:

• A healthcare professional collects a small blood sample from a vein in your arm.
• The sample is analysed in the laboratory using advanced immunoassay techniques (e.g., CLIA).
• Results are generally available within 3 to 5 working days.

When Should You Get the Test Done?

• Ideally between 10 and 13 weeks of pregnancy, alongside the NT ultrasound.
• May be combined with other maternal screening tests for comprehensive evaluation.

Test Frequency

This is a one-time screening during the first trimester. If results are inconclusive or high-risk, further tests like NIPT or Triple Marker/Quadruple Marker in the second trimester may be recommended.

Booking the Double Marker with PLGF Test Online & Accessing Reports

Booking the Double Marker with PLGF Test online is a fast, convenient way to arrange home sample collection from your doorstep, pay securely and access your detailed report electronically,making it easier to take control of your health screening.

Steps to Book the Double Marker with PLGF Test:

• Visit the Apollo 24|7 website or app.
• Search for “Double Marker with PLGF Test.”
• Check test price and availability in your city.
• Schedule a convenient appointment (home collection or lab visit).
• Complete secure online payment.

Accessing Your Report:

• Log in to your Apollo 24|7 account.
• Go to ‘My Reports’ or ‘Health Records’.
• Download your digital report in PDF format.
• Share it with your gynaecologist for interpretation and advice.

Importance of Early Screening

Early maternal serum screening offers multiple benefits:

• Early Detection of Chromosomal Abnormalities: Identifies potential risks such as Down syndrome or Edwards syndrome in the first trimester, allowing timely follow-up with confirmatory tests and early medical guidance.
• Assessment of Placental Health: The addition of PLGF helps evaluate placental function, enabling early prediction of complications like preeclampsia or restricted foetal growth.
• Non-Invasive and Safe: As a simple blood test, it poses no risk to the mother or baby, making it a safe and stress-free option for prenatal risk assessment.
• Guides Pregnancy Management: Early results help doctors personalise antenatal care, monitor high-risk pregnancies more closely, and plan preventive interventions if required.
• Reduces Anxiety for Expectant Parents: Low-risk results provide reassurance and peace of mind, while high-risk results encourage informed decision-making and timely action.
• Improves Foetal Outcomes: Early identification and monitoring of high-risk conditions help ensure better maternal health and improved chances of a healthy pregnancy and delivery.

Conclusion

The Maternal Serum Screening – Double Marker with PLGF Test is a reliable, non-invasive tool that helps identify early pregnancy risks, including chromosomal abnormalities and placental dysfunction. By integrating PLGF with traditional biochemical markers, this test improves the accuracy of first-trimester screening and aids clinicians in providing personalised pregnancy care. With Apollo 24|7, you can easily book the test online, avail home collection, and access NABL-accredited results from the comfort of your home. Early screening empowers parents and healthcare providers to take proactive steps for a healthy pregnancy and a safe delivery.