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Neuronal (Paraneoplastic) Autoantibodies Profile

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  • NEURONAL (PARANEOPLASTIC) AUTOANTIBODIES PROFILE

    1 test included

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About

blood sample
Sample

BLOOD

Gender
Gender

Both

users
Age group

7 years & above

The neuronal autoantibodies profile test analyses the presence of antibodies that become active during paraneoplastic syndromes (PNS). These syndromes or disorders can initiate from tumours like small cell lung carcinoma (SCLC), breast cancer, thymoma, or ovarian cancer.

This test helps evaluate paraneoplastic syndromes associated with the nervous system. The test results can detect the presence of the following antibodies:

  • Anti-Hu
  • Anti-Yo
  • Anti-Ri
  • Anti-Tr
  • Amphiphysin
  • Titin
  • Recoverin

Each of these antibodies is associated with distinct tumours. The neuronal autoantibodies profile test determines the occurrence of such autoantibodies.

In addition to blood tests and spinal tap, your doctor can also conduct a clinical exam. This clinical evaluation can include questions related to your reflexes, balance, mood, vision, muscle strength, memory, etc.

Why Should You Get Tested?

Paraneoplastic syndromes are generally associated with different types of cancers. So, it is very important to follow all medical protocols for early detection and diagnosis.

The neuronal autoantibodies profile generates a comprehensive report related to the nervous system. Diseases associated with the nervous system can hamper your daily functioning. Delay in the detection of these autoantibodies can aggravate the symptoms to a great extent. Hence, it is crucial to follow your doctor’s advice and consider a professional neuronal autoantibodies test profile.
 

faqFrequently Asked Questions (FAQs)

No, there are no such risks associated with the Neuronal (Paraneoplastic) Autoantibodies Profile Test. The test uses a blood sample, which is extracted from your arm vein with the help of a needle. Hence, you might experience some light bleeding or scarring at the point of contact with the needle.
Here are some initial signs that announce the onset of a brain tumour: Constant headaches Unexplained vomiting or nausea Difficulty balancing  Vision problems Loss of sensation or movement in arm or leg
In case your body experiences a break in tolerance against self-antigens, it will produce autoantibodies. But what causes this tolerance break? Well, it might be due to inflammation-mediated modification of the self-antigen, deficit in the clearance of apoptotic debris, etc.
Self-antigens are made up of fats, carbohydrates, nucleic acids, or proteins and can be tissue-specific. They could also be found in all cell types.
Yes, you can treat autoantibodies with Intravenous Immunoglobulin (IVIG). It is prepared from antibodies of healthy donors and is used in controlled amounts to treat patients with low antibody levels.
Here is a list of cancers that can cause neurological issues: Melanoma  Lung cancer Breast cancer Non-Hodgkin’s Lymphoma  Cancers that metastasize to the CNS (Central Nervous System) or spine

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results