NIPT 5 Chromosome (21, 13, 18, X, Y) Test

Test Overview

The NIPT 5 Chromosome (21, 13, 18, X, Y) Test is a highly advanced, non-invasive prenatal screening designed to evaluate the risk of specific chromosomal abnormalities in a developing foetus. It primarily focuses on five major chromosomes — 21, 13, 18, X, and Y, which are associated with well-known genetic conditions such as Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), Patau syndrome (Trisomy 13), and certain sex chromosome abnormalities like Turner and Klinefelter syndromes.

This sophisticated screening test works by analysing cell-free foetal DNA (cfDNA) circulating in the mother's bloodstream. From as early as the 10th week of pregnancy, a simple maternal blood sample can provide crucial insights into the baby’s chromosomal health, all without posing any risk to the mother or foetus. The test identifies whether there are extra or missing copies of these chromosomes, which may indicate the likelihood of a chromosomal disorder. Although the NIPT 5 Chromosome Test is not diagnostic, it provides high sensitivity and specificity, making it a reliable first-line screening option for expectant parents.

What is the NIPT 5 Chromosome (21, 13, 18, X, Y) Test Price?

The NIPT 5 Chromosome Test is a premium prenatal screening, and its price may vary based on several factors such as location, lab quality, and additional services.

• Location: Costs differ between cities, metros like Mumbai, Delhi, Bengaluru, and Hyderabad usually offer more options and competitive pricing.
• Scope of Testing: This panel screens five key chromosomes (21, 13, 18, X, Y). Extended panels covering more genetic conditions may cost extra.
• Lab Accreditation & Technology: NABL- or CAP-accredited labs using advanced sequencing systems ensure accuracy and reliability, sometimes at a higher price.
• Sample Collection & Counselling: The cost usually includes blood collection, DNA analysis, and reporting. Some centres may offer genetic counselling as part of the package.
• Discounts & Offers: Platforms like Apollo 24|7 often provide bundled maternity packages or special discounts.

For the latest and most accurate NIPT 5 Chromosome Test price near you, visit the Apollo 24|7 website or app and consult your doctor before booking.

What is the Purpose of the NIPT 5 Chromosome (21, 13, 18, X, Y) Test?

The main purpose of the NIPT 5 Chromosome Test is to screen for common chromosomal abnormalities early in pregnancy. It helps doctors and parents assess potential risks and make well-informed decisions about further testing and pregnancy management.

1. Screening for Common Chromosomal Disorders

This test screens for:

• Trisomy 21 (Down syndrome): Linked with developmental delays and characteristic physical features.
• Trisomy 18 (Edwards syndrome): Associated with severe growth restriction and congenital anomalies.
• Trisomy 13 (Patau syndrome): A rare but serious disorder causing multiple structural abnormalities.

Early identification of these conditions enables timely follow-up diagnostic tests and the opportunity for tailored medical or emotional support.

2. Detecting Sex Chromosome Abnormalities

The test screens the X and Y chromosomes for conditions like Turner syndrome and Klinefelter syndrome, helping identify potential hormonal, developmental, or reproductive issues early for timely care.

3. Enabling Early Risk Assessment

Conducted from the 10th week of pregnancy, this test provides an early and accurate genetic assessment, especially useful for women with high-risk pregnancies or a family history of chromosomal disorders.

4. Reducing the Need for Invasive Procedures

With over 99% accuracy for detecting common trisomies, NIPT significantly reduces the need for invasive procedures like amniocentesis or CVS, which carry a small miscarriage risk.

5. Supporting Informed Pregnancy Planning

If results show a high risk, parents can consult genetic experts to decide next steps. Whether confirming reassurance or guiding further testing, it supports well-informed and confident decisions during pregnancy.

Who Should Get an NIPT 5 Chromosome (21, 13, 18, X, Y) Test Done?

The NIPT 5 Chromosome Test is suitable for almost all expecting mothers, though it is particularly valuable for certain risk groups:
Women aged 35 or older: Advanced maternal age increases the likelihood of chromosomal abnormalities, making early screening crucial.

• Individuals with a family history of genetic conditions: If chromosomal disorders are present in family history, this test can provide early reassurance.
• Abnormal first-trimester screening or ultrasound findings: If standard prenatal tests indicate potential abnormalities, NIPT serves as a safer follow-up.
• Pregnancies conceived through IVF: Helps confirm genetic health in assisted conceptions.
• History of chromosomal abnormalities in prior pregnancies: Recommended for those with previous experiences of affected pregnancies.
• General reassurance: Even low-risk expectant parents often opt for NIPT for peace of mind, given its safety and reliability.

Components of an NIPT 5 Chromosome (21, 13, 18, X, Y) Test

The NIPT 5 Chromosome Test specifically analyses the following chromosomes, each associated with distinct conditions:
 

B. How to Interpret the Chromosome Results?

Note: Results should always be reviewed by a qualified genetic counsellor or obstetrician. If a high-risk result is detected, your doctor may recommend confirmatory diagnostic tests such as amniocentesis or CVS, depending on gestational age and clinical factors.

Preparation and Procedure for NIPT 5 Chromosome (21, 13, 18, X, Y) Test

Before taking the test, understanding the preparation steps and sample collection procedure ensures a smooth experience and accurate results.

A. How is the Test Done?

The NIPT 5 Chromosome Test is completely non-invasive and safe for both mother and baby.

• A trained phlebotomist collects a blood sample from the mother’s arm, typically between 10–13 weeks of pregnancy.
• The sample contains cell-free foetal DNA fragments circulating in maternal blood.
• In the laboratory, this DNA is extracted and analysed using advanced sequencing and bioinformatics methods to identify any extra or missing copies of chromosomes 21, 13, 18, X, and Y.
• The entire process takes just a few minutes and poses no physical risk to the foetus or mother.
• Once the results are ready, they are reviewed by your doctor, who will explain the findings and any recommended next steps.

B. Is Fasting Required?

No fasting is required before this test. You may eat and drink as usual. Staying well-hydrated is advised as it helps with smoother blood collection.

C. Best Time for the Test

The test can be conducted at any time during clinic or laboratory hours. However, morning appointments are often preferred for quicker processing and same-day sample dispatch.

D. How Often Should the Test Be Taken?

The NIPT 5 Chromosome Test is generally done once per pregnancy, ideally between the 10th and 13th week. A repeat test may be required only if the results are inconclusive or additional analysis is advised by your doctor.

Booking NIPT 5 Chromosome (21, 13, 18, X, Y) Test Online & Checking Reports

Booking the NIPT 5 Chromosome Test through Apollo 24|7 is straightforward and convenient. Here’s how to schedule your test and access your reports online:

A. How to Book the Test Online?

• Visit Apollo 24|7: Access the platform via the website or mobile app.
• Search for the Test: Use the search bar and type “NIPT 5 Chromosome (21, 13, 18, X, Y) Test” to find the specific test page.
• Check Price and Availability: Confirm the latest test price for your city and choose your preferred collection method.
• Select Time and Location: Choose a convenient time slot and decide between home sample collection or a nearby diagnostic centre.
• Provide Details and Confirm Booking: Enter your personal and appointment details, complete secure online payment, and receive booking confirmation.

B. How to Access Your Test Results?

Once the test is complete, you can easily view your results online:

• Receive Notification: Apollo 24|7 will notify you when your report is ready.
• Log in to Your Account: Use your registered credentials on the website or app.
• Navigate to “My Reports”: Access your test reports under the Health Records section.
• View and Download Report: Click on your NIPT 5 Chromosome Test report to view detailed results and download a PDF copy for your records or doctor’s consultation.
• Reports are typically available within 7–10 working days after sample collection.

Conclusion

The NIPT 5 Chromosome (21, 13, 18, X, Y) Test is a breakthrough in prenatal genetic screening, offering expectant parents a safe, accurate, and early method to assess the baby’s chromosomal health. By analysing just a small sample of maternal blood, this test delivers vital information about the risk of conditions like Down, Edwards, and Patau syndromes, as well as sex chromosome abnormalities. If you’re searching for a “NIPT 5 Chromosome test near me,” Apollo 24|7 provides reliable, accredited laboratory testing with convenient home collection and online report access. Book your test today and take a confident step towards ensuring a healthy and well-informed pregnancy journey.