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Porphobilinogen - Spot Urine(Qualitative Screen) in Kukatpally Housing Board Colony, Hyderabad

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  • Porphobilinogen - Spot Urine(Qualitative Screen)

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About

blood sample
Sample

URINE

Gender
Gender

Both

users
Age group

7 years & above

Porphobilinogen is one of the many types of porphyrins present in our body that help in the formation of haemoglobin. The substance usually exits the body through urine, but sometimes the process fails and leads to its build-up.

This build-up of Porphobilinogen might lead to health issues like Porphyria or Acute intermittent porphyria (AIP). It is a metabolic disorder that is caused by the deficiency of an enzyme called porphobilinogen deaminase (PBGD). Further, this deficiency can lead build-up of porphyrin precursors in your body, which might be toxic.

Most people do not experience Acute intermittent porphyria symptoms, but certain factors might trigger the health conditions. These triggers might include excessive consumption of alcohol, dietary changes, and specific drugs.

Acute porphyrias cause health complications that might affect your nervous system. There are various Acute intermittent porphyria symptoms that might last for a few days to weeks.

  • High blood pressure 
  • Breathing problems 
  • Pain in the abdomen 
  • Diarrhoea 
  • Constipation 
  • Vomiting and nausea 
  • Problems during urination 
  • Numbness, weakness and even paralysis in your muscles 
  • Irregular heartbeats 
  • Mental problems such as hallucination, paranoia, anxiety and confusion 
  • Insomnia

As Acute intermittent porphyria symptoms vary from patient to patient, ignoring them can be fatal. So, it is essential to seek medical supervision when you experience these symptoms. Doctors consider the Porphobilinogen - Spot Urine (Qualitative Screen) Test the most suitable test to detect Acute intermittent Porphyria.

This test is an examination of the abnormalities caused due to reactions involving heme synthesis. The complications and reactions might occur in your bone marrow or the hepatic synthesis sites. The doctor will analyze your urine sample in this test to understand the concentration of Porphobilinogen in it.

The Porphobilinogen - Spot Urine (Qualitative Screen) Test will also aid doctors in assessing other diseases associated with Porphyria. Moreover, they will also analyze the reasons behind your abnormal Porphobilinogen levels. A doctor may also conduct the urine Porphobilinogen test procedure to detect the porphyria acute attack types which might be linked to psychiatric or neurologic disorders. They comprehend this by analysing the sample and the respective porphyrin Urias.

If the test detects the presence of aminolevulinic acid and Porphobilinogen in your urine, the chances of acute intermittent Porphyria are high. After examining your Porphobilinogen levels, the doctor will check your Acute intermittent porphyria symptoms. He/She might ask you about the symptoms or issues that you might be experiencing. You should also disclose information about any medications you may be consuming and any recent changes to lifestyle.

Before taking the Porphobilinogen - Spot Urine (Qualitative Screen) Test, ask the doctor about the dietary restrictions for the process. To experience a hassle-free test, opt for it online at Apollo 24|7.    
 

faqFrequently Asked Questions (FAQs)

The doctor will require your urine sample for conducting the test. He or she will give you all the instructions and restrictions for the test. You might talk to the doctor about the drugs you should avoid before the Porphobilinogen - Spot Urine (Qualitative Screen) Test.
For the Porphobilinogen test, the normal Porphobilinogen level is 4 milligrams per 24 hours. It is applicable to a 24-hour urine sample. In the case of a random urine sample, negative test results are normal. Still, these normal values may differ as per the lab testing of the sample.
Acute intermittent Porphyria can lead to severe health complications like kidney diseases, high blood pressure, skin issues, breathing problems and dehydration. It is recommended that you consult a doctor immediately to prevent an attack of Porphyria. Medical consultation will also prevent the Porphobilinogen levels from increasing as the doctor begins treatment.
You can prevent the triggers for Acute intermittent porphyria symptoms by using drugs only after medical consultation. You must also avoid smoking, alcohol, and recreational drugs. Also, if you're dieting, do it after discussing it with your doctor. It is also advised that you treat infections immediately to prevent porphyria symptoms.
You will receive the test results within 24 to 48 hours. However, if the doctor needs additional tests, the urine Porphobilinogen test procedure will take longer.
There are no specific strategies to prepare for the Porphobilinogen - Spot Urine (Qualitative Screen) Test. However, to provide a 24-hour urine sample, consult your doctor for instructions.

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results