Anti Smooth Muscle Antibody - Titre (Asma)

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    blood sample




    Age group

    Above 10 years

    An Anti-Smooth Muscle Antibody (ASMA) test identifies autoantibodies that damage smooth muscle cells in the body, most commonly in the liver. Autoantibodies are antibodies directed against the body’s cells.

    Normally, your immune mechanism will use antibodies to defend your body against foreign substances such as bacteria or viruses. ASMAs and other autoantibodies mistake the body’s cells and tissues for foreign objects and instruct your immune system to attack them.

    Smooth muscle antibodies, commonly known as ASMAs, target smooth muscle tissues in various body parts. The liver's smooth muscle tissues are the most common target for ASMAs. ASMA testing looks for these antibodies in the bloodstream.

    Smooth muscle antibodies can be discovered in people who have:

    • Infectious illnesses  
    • Hepatitis  
    • Rheumatoid problem
    • Cancer

    Apollo 24|7's Anti-Smooth Muscle Antibody test can be used to assess individuals with longstanding liver disease suspected of having chronic active autoimmune hepatitis. Alcoholic hepatitis, chronic viral hepatitis, and primary biliary cirrhosis are also among conditions where it might be used. In people with chronic active hepatitis, antibody titres in the 80-320 range are normal.

    Low anti-smooth muscle antibody titres have been linked to viral illnesses that cause Hypogammaglobulinemia. Connective tissue disorders and persistent infections typically have lower levels.

    Immunosuppressive medicines can be used to treat autoimmune hepatitis if it is discovered early. It can lead to hepatic failure if not treated timely. Even though autoimmune hepatitis can affect anybody, it is more prevalent among women.

    Talk to your physician or healthcare professional about undergoing ASMA testing. A few of the most common symptoms include:

    • Nausea  
    • Appetite fluctuations  
    • Yellow-tinted skin and eyes 
    • Stomach ache 
    • Joint pain or discomfort  
    • Allergic reactions

    Your physician might want you to get regular blood tests, including the Anti-Smooth Muscle Antibody test and other testing, to ensure your liver is in good shape. If the symptoms of autoimmune hepatitis become more frequent and severe, your doctor may recommend that you begin treatment.

    Steroids are frequently used as a first-line treatment for this condition, which impairs your immune system and may cause weight gain, a decrease in the density of white blood cells, and damaged bones. Some patients require years of treatment before their symptoms go away completely. However, if symptoms reappear, treatment must be repeated.

    It's difficult to predict the long-term implications of ASMAs, particularly autoimmune hepatitis. The illness could be acute or persistent. If you get a positive Anti-Smooth Muscle Antibody test, you should seek treatment from a doctor who specialises in liver issues and autoimmune diseases.

    Apollo 24|7 offers an effective Anti-Smooth Muscle Antibody test, which can be used to:

    • Detect the existence of anti-smooth muscle antibodies 
    • Assess your ASMA levels regularly to help your doctor build an appropriate treatment plan 
    • Diagnose autoimmune hepatitis

    faqFrequently Asked Questions (FAQs)

    Frequently asked questions

    During the test procedure, a tiny needle is used to obtain a blood specimen from a vein in your arm. A modest quantity of blood is collected in a vial or container once the syringe is inserted. When the syringe goes in or out, it may sting a little. It usually takes less than 5 minutes to complete this procedure.
    A blood test is not that risky. You may experience slight pain or redness where the syringe was inserted, however, most effects fade quickly.
    If you have a substantial concentration of smooth muscle antibodies in your blood, you most likely have type 1 autoimmune hepatitis. A lower number could indicate that you have type 2 of the ailment. If no SMAs are discovered, your liver concerns are likely due to something other than autoimmune hepatitis. To make a diagnosis, your doctor may need to request more testing.
    The Anti-Smooth Muscle Antibody test is generally used to determine whether someone has autoimmune hepatitis. It's also used to determine whether the condition is type 1 or 2. ASMA testing is frequently performed in conjunction with other tests to verify or eliminate an autoimmune hepatitis diagnosis.
    A negative ASMA testing combined with a high LKM1 titer could indicate autoimmune hepatitis type 2. If the ASMA test, as well as other antibody tests, come back negative, the ailments and liver damage could be caused by anything other than autoimmune hepatitis.
    While fasting overnight before an Anti-Smooth Muscle Antibody test is suggested, it is not mandatory. Your physician may advise you on additional dietary restrictions for the test.

    Why should Apollo be your preferred healthcare partner?

    • 40 Years of legacy and credibility in the healthcare industry.
    • NABL certified multi-channel digital healthcare platform.
    • Affordable diagnostic solutions with timely and accurate test results.
    • Up to 60% discount on Doorstep Diagnostic Tests, Home Sample Collection.
    • An inventory of over 100+ laboratories, spread across the country, operating out of 120+ cities with 1200+ collection centers, serving over 1800+ pin codes.

    The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results