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Toxoplasma Avidity IgG in I E Nacharam, Hyderabad

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7 years & above

Toxoplasmosis is an ailment caused by Toxoplasma gondii, one of the most commonly encountered parasites in the world. The disease usually spreads by either eating undercooked meat, exposure to infected faeces of cats, or genetics, where it passed from the mother to the child during pregnancy.

It is especially fatal during pregnancy since the parasites might be transmitted through the placenta. The foetus can sustain severe damage before the development of toxoplasma-specific antibodies. However, if this infection is contracted before pregnancy, it poses no threat to the foetus since the maternal antibodies protect it.

People with weakened immune systems, especially those with HIV and AIDS, are also at significant risk for toxoplasmosis. Hence, it is vital to differentiate between the acute and chronic stages of the disease to reduce its effects and to chart out an adequate treatment plan.

Since it is difficult to isolate the parasite, the diagnosis is usually made via serological methods. The toxoplasma avidity IgG test is the standard blood test that checks for toxoplasma-specific antibodies in the blood. The testing requires only a blood sample.

For pregnant women, the doctor will take a sample of the amniotic fluid and the foetus’s blood. The doctor then studies the samples to determine if the infection has been transmitted to the foetus.

The avidity IgG test is primarily responsible for measuring the antibody binding force, which differs depending on the time of the infection.

  • The antibody binding force is low in the early stage after the primary infection occurs
  • A high avidity IgG test signals that the infection likely occurred around 4 months ago

IgG antibodies are notorious for appearing a few weeks after the toxoplasmosis infection and may remain in the body forever. But the blood test can detect these antibodies almost instantly.

Apollo 24|7 offers a comprehensive toxoplasma avidity IgG test to determine the presence of the infection in the body. Although the toxoplasmosis infection is mainly asymptomatic, the few visible symptoms associated with it are similar to that of flu. Some of these include:

  • Body aches
  • Swollen lymph nodes
  • Headache
  • Fever
  • Fatigue

These symptoms may differ in individuals with weakened immune systems. They may encounter the following symptoms:

  • Lung problems akin to tuberculosis 
  • Poor coordination
  • Seizures
  • Retinal inflammation leading to blurred vision
  • Confusion
  • Constant headache

Children might also contract a toxoplasmosis infection from their mothers and may display symptoms like severe eye infections and yellowing of the skin. 
 

Medically reviewed by Dr. Ravikiran Barigala, Infectious disease, Apollo Hospitals Jubilee Hills, Hyderabad.

faqFrequently Asked Questions (FAQs)

What happens if toxoplasmosis is left untreated?

A toxoplasmosis infection is caused by a lethal fungus called Toxoplasma gondii. If left untreated, it has the potential to cause eye infections, which might eventually cause blindness in healthy people. If you have a weakened immune system, this condition can lead to seizures and fatal brain infections.

What does avidity mean? What is its significance in the test for toxoplasmosis?

Avidity is the total binding strength between an antibody and an antigen. High avidity suggests that the toxoplasmosis infection was acquired around three months ago since the antibody binding force is low in the early stage. On the other hand, a low avidity suggests that the infection is relatively recent.

What do IgG and IgM mean in toxoplasmosis?

When you first have a toxoplasmosis infection, the body produces measurable Immunoglobin M (IgM) antibodies in the blood. This usually happens 1 to 2 weeks after the infection. Gradually, IgM antibodies fade, and Immunoglobin G (IgG) antibodies take their place. IgG antibodies remain in the body forever, and IgM antibodies may resurface, especially if the infection is reactivated or chronic.

Does the toxoplasma avidity IgG test have any side effects?

Blood tests like the toxoplasma avidity IgG test pose little to no risks. At most, there might be slight bruising at the spot where blood is drawn, but it fades away rapidly without any intervention.

When are you most susceptible to health complications from toxoplasmosis?

The Toxoplasma gondii bacteria is usually present in uncooked meat and cat faeces. Any exposure to these can lead to toxoplasmosis. Individuals who are most susceptible to significant health issues from this infection are: Patients suffering from HIV/AIDS People undergoing chemotherapy Individuals taking steroids or other immunosuppressants to treat certain non-malignant conditions

How soon are the toxoplasma avidity IgG test results available?

The results of the toxoplasma avidity IgG test depend on the lab in which you get the test done. However, the standard wait time for the results is about 36 hours after the test is done.

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results