VMA(Vanillyl Mandelic Acid)- Spot Urine in New-alipore, Kolkata
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Test(s) Included (1)
- VANILLYL MANDELIC ACID (VMA) - SPOT URINE
1 test included
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URINE

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7 years & above
VMA (Vanillyl Mandelic Acid) - Spot Urine: Price, Purpose, Range & Reports
Test Overview
| Sample Type | Blood |
| Report Delivery | Earliest reports available within 48 hours |
| Price/Cost | 4250 |
| Number of Tests Included | 1 |
The VMA (Vanillyl Mandelic Acid) - Spot Urine Test is a diagnostic tool used to screen for tumours that produce excess catecholamines (hormones like adrenaline and noradrenaline). VMA is the final major breakdown product (metabolite) of these hormones. This test is primarily ordered to investigate symptoms related to rare adrenal gland tumours, such as pheochromocytoma, and nerve tissue tumours, such as neuroblastoma in children.
By measuring the concentration of VMA in a single (spot) urine sample, and often normalising it against the creatinine level to account for urine dilution, healthcare providers can assess potential overproduction of catecholamines. If you are searching for a reliable VMA (Vanillyl Mandelic Acid) - Spot Urine Test price or a convenient test near me, Apollo 24|7 provides accredited laboratory services with timely collection and secure, fast report access.
What is the VMA (Vanillyl Mandelic Acid) - Spot Urine Test?
The VMA (Vanillyl Mandelic Acid) - Spot Urine Test measures the amount of Vanillyl Mandelic Acid excreted in the urine. VMA is an important chemical intermediary created when the body metabolises, or breaks down, catecholamines such as epinephrine (adrenaline) and norepinephrine (noradrenaline). These catecholamines are vital stress hormones produced by the adrenal glands and the nervous system. The test is a non-invasive way to measure their activity.
This test is crucial for patients presenting with classic symptoms of catecholamine excess, including episodic or persistent high blood pressure, unexplained anxiety, rapid heart rate (tachycardia), and severe headaches accompanied by excessive sweating. While VMA is traditionally measured using a 24-hour urine collection, the Spot Urine test offers a faster and simpler sample collection for screening purposes. However, the interpretation of the spot sample is highly dependent on strict pre-test preparation, especially dietary and medication restrictions.
What is the VMA (Vanillyl Mandelic Acid) - Spot Urine Test Price?
The VMA (Vanillyl Mandelic Acid) - Spot Urine Test price reflects the complexity of the analytical method required to measure VMA accurately. VMA analysis is not a routine chemistry test, and its cost is influenced by the following factors:
- Technology Used: The test often requires advanced analytical platforms such as High-Performance Liquid Chromatography (HPLC) or Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) to separate and precisely quantify VMA from other interfering compounds.
- Location and Logistics: Regional operating expenses and the necessary refrigerated handling of the urine sample from collection to the testing laboratory can influence the final price.
- Service Type: Whether you choose to provide the spot urine sample at a collection centre or opt for the convenience of home sample collection may affect the total cost.
- Lab Quality and Accreditation: Tests performed at labs with national accreditations (like NABL) ensure rigorous quality control, which adds confidence to the result's accuracy, particularly for rare tumour markers.
For the most up-to-date and competitive VMA (Vanillyl Mandelic Acid) - Spot Urine Test price near me, you can check the Apollo 24|7 website or app. Prices are regularly updated based on your location and include all applicable offers.
Who Needs a VMA (Vanillyl Mandelic Acid) - Spot Urine Test?
A healthcare provider typically orders this test when there is a suspicion of a catecholamine-producing tumour, which is are rare but potentially serious condition.
You should consider getting tested or discussing this test with your doctor if you experience the following persistent or episodic symptoms:
- Episodic or Sustained High Blood Pressure: Especially if standard treatments are ineffective or if the hypertension is sudden and severe.
- Sudden, Severe Headaches: Often described as throbbing or pounding.
- Rapid or Pounding Heartbeat (Palpitations): Unexplained episodes of tachycardia.
- Excessive Sweating: Often without a clear cause, like exercise or heat.
- Unexplained Anxiety or Panic Attacks: Symptoms that mimic anxiety but have a physical rather than psychological root.
- Children with Suspected Neuroblastoma: This tumour primarily affects young children, and VMA is an important screening marker.
- Monitoring Patients: Individuals who have already been treated for pheochromocytoma or neuroblastoma may undergo this test periodically to check for recurrence.
What is the Purpose of the Test?
The primary purposes of performing the VMA (Vanillyl Mandelic Acid) - Spot Urine Test are:
- Screening for Pheochromocytoma: To detect this rare tumour of the adrenal medulla, which causes overproduction of adrenaline and noradrenaline.
- Screening for Neuroblastoma: To help diagnose this cancer of the nervous system, typically seen in infants and young children, which also often results in elevated VMA.
- Monitoring Treatment Efficacy: To track VMA levels after surgical removal or treatment of these tumours, ensuring the treatment has been effective.
- Investigating Symptoms: To evaluate patients presenting with symptoms suggestive of catecholamine excess, helping to confirm or rule out a hormonal cause.
Components of the VMA (Vanillyl Mandelic Acid) - Spot Urine Test
The VMA (Vanillyl Mandelic Acid) - Spot Urine Test involves the measurement of two key components:
- Vanillyl Mandelic Acid (VMA): The VMA Spot Urine Test measures the level of vanillylmandelic acid (VMA), a substance produced when the body breaks down catecholamines such as adrenaline and noradrenaline. This test is often used to help detect certain rare tumours, including pheochromocytoma and neuroblastoma, which can cause elevated catecholamine levels.
Understanding a VMA (Vanillyl Mandelic Acid) - Spot Urine Test Report
While reference ranges may vary slightly between laboratories, a commonly accepted normal range for VMA in a spot urine sample is:
- Children: 1.0 – 7.0 mg/g creatinine
- Adults: 1.0 – 8.0 mg/g creatinine
Your result will typically fall into one of the following categories:
Important Considerations
- Diet and medications can affect VMA levels. Foods such as bananas, vanilla, chocolate, and caffeine, as well as certain medications, may influence results. Your healthcare provider may advise dietary restrictions before testing.
- Spot urine samples are convenient but may be less comprehensive than 24-hour urine collections. If results are borderline or inconsistent, additional testing may be needed.
- VMA levels should always be interpreted by a healthcare provider in combination with your symptoms, medical history, and other diagnostic tests.
Preparation and Procedure for VMA (Vanillyl Mandelic Acid) - Spot Urine Test
Preparation is the most critical factor for ensuring the accuracy of the VMA test, as many common foods and medications can interfere with the results.
1. How is the Test Done?
- The test requires a single (spot) urine sample.
- A sterile collection container will be provided.
- Simply collect a sample of urine in the container at any time of day (though your doctor may specify morning collection).
- The sample is then sealed and sent to the laboratory under proper refrigeration immediately.
2. Dietary and Medication Restrictions (Crucial)
Strict adherence to these preparation steps for 2-3 days prior to collection and on the day of collection is mandatory:
- Avoid Interfering Foods: Eliminate foods high in VMA or its precursors, including coffee, tea, chocolate, bananas, vanilla, citrus fruits, and nuts.
- Avoid Interfering Medications: Discuss all medications with your doctor. They may ask you to temporarily stop (for 2-3 days) drugs like aspirin, cold medications, lithium, reserpine, and certain antihypertensives, as they can interfere with VMA measurement. Never stop any medication without consulting your doctor.
- Avoid Stress: Physical or emotional stress can artificially raise catecholamine levels, leading to a false high result. Try to remain calm and relaxed before and during the collection period.
3. Is Fasting Required for This Test?
No, strict fasting is not required, but the mandatory dietary restrictions (avoiding specific foods/drinks listed above) are far more important than fasting for this particular test.
4. What Time of the Day Should I Undergo the Test?
The test requires a spot urine sample taken at any time; however, due to the need for strict preparation, your doctor may recommend a specific time that minimises exposure to interfering substances or when symptoms are most likely to occur.
Booking VMA (Vanillyl Mandelic Acid) - Spot Urine Test Online & Checking Reports
Apollo 24|7 provides a convenient and confidential way to schedule your VMA Spot Urine Test and access your results quickly.
A. What are the Steps to Schedule the Test on Apollo 24|7?
- Visit the Apollo 24|7 website or mobile application and search for the VMA Spot Urine test (or use the full name Vanillyl Mandelic Acid - Spot Urine).
- Confirm the latest VMA (Vanillyl Mandelic Acid) - Spot Urine Test price for your city and click the 'Book Now' button.
- Select your preferred date and a convenient time slot for the sample collection.
- Complete the secure online payment. Confirmation details and a detailed list of preparation instructions will be sent instantly.
B. How Do I Access My Test Results Online on Apollo 24|7?
- Log in to your Apollo 24|7 account using your registered phone number or email.
- Navigate to the 'Health Records' or 'My Reports' section on the dashboard.
- Click on your completed test name to view the detailed report immediately.
- You can easily view the entire report online or download it in PDF format to share with your physician.
Conclusion
The VMA (Vanillyl Mandelic Acid) - Spot Urine Test is a critical, high-accuracy screening tool for detecting rare but potentially life-threatening tumours, such as pheochromocytoma and neuroblastoma. Because the VMA result is a direct measurement of catecholamine metabolism, its accuracy relies entirely on the patient's strict adherence to dietary and medication restrictions prior to collection. An elevated VMA level serves as a crucial indicator that requires immediate follow-up and comprehensive diagnostic confirmation by a specialist. By providing reliable testing services, this assay assists clinicians in rapidly investigating symptoms related to catecholamine excess and initiating life-saving treatment.
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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results

