I was diagnosed with right breast IDC grade III and am BRCA1 positive. After NACT with 4AC followed by 12 Paclitaxel, I had a bilateral modified radical mastectomy left breast removed as prophylaxis. The biopsy report shows clear lymph nodes and left breast, with post-NACT improvement on the right but some residual disease. Should I keep taking Tamoxifen 20mg after surgery? My periods have stopped will they come back if I stop Tamoxifen? Also, is oophorectomy recommended in my case? My post-NACT PET CT showed an enlarged hypoechoic right cervical lymph node (2x1.3 cm) is this something to worry about or just normal?

Answered by 1 Apollo Doctors

Dr Dhankecha Dineshbhai

General Practitioner

MBBS
6+ Yrs

Consult Now

Tamoxifen is typically prescribed for ER-positive breast cancer to reduce the risk of recurrence. Stopping it may affect your hormonal balance, and periods may not return. An oophorectomy might be considered in high-risk cases like yours. Discuss this with your oncologist.

Dr. Dhankecha Suggests...

Consult a Oncologist

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Answered 14/08/2025

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Tamoxifen is typically prescribed for ER-positive breast cancer to reduce the risk of recurrence. Stopping it may affect your hormonal balance, and periods may not return. An oophorectomy might be considered in high-risk cases like yours. Discuss this with your oncologist.

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