I'm a 33-year-old guy and I've been using Minokem N 5 lotion, which has Minoxidil, Azelaic acid, and Tretinoin, for about 7 years now. While my hair loss seems under control, I haven't seen any major hair growth. So far, I haven't experienced any side effects, but I'm a bit worried about whether there could be any long-term effects if I keep using this. Is this combo safe to use indefinitely, or should I be looking out for any specific issues?

Answered by 1 Apollo Doctors

Dr Dhankecha Dineshbhai

General Practitioner

MBBS
6+ Yrs

Consult Now

Long-term use of Minokem N 5% lotion (Minoxidil + Azelaic acid + Tretinoin) may lead to potential side effects, such as skin irritation, dryness, or allergic reactions, although rare; while minoxidil is generally safe for long-term use, azelaic acid and tretinoin may increase skin sensitivity, and prolonged use of tretinoin can lead to skin thinning or increased risk of skin cancer; consult a dermatologist to assess your individual risk-benefit profile and determine if lifelong use is advisable, considering regular monitoring and potential adjustments to your treatment plan.

Dr. Dhankecha Suggests...

Consult a Dermatologist

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Answered 04/07/2025

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Disclaimer: Answers on Apollo 247 are not intended to replace your doctor advice. Always seek help of a professional doctor in case of an medical emergency or ailment.