I'm a bit concerned about my homocysteine level, which is currently at 29.9. Is this considered normal, or should I be worried? What could be causing it to be so high? Any advice would be really appreciated.

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Dr Anshul Maheshwari

General Practitioner

MBBS
5+ Yrs

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Homocysteine level of 29.9 is considered high. Possible causes of increased homocysteine levels include vitamin deficiencies (B6, B12, and folate), kidney disease, hypothyroidism, psoriasis, certain medications (such as methotrexate), and genetic factors. To lower homocysteine levels, you can consider taking medications like folic acid, vitamin B6, and vitamin B12. The recommended dosage of folic acid is usually 400-800 mcg per day, vitamin B6 is 1.3-1.7 mg per day, and vitamin B12 is 2.4 mcg per day.

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Answered 04/07/2025

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Homocysteine Level Assessment
- A homocysteine level of 29.9 is significantly elevated. Normal levels are typically below 15 µmol/L.
Potential Causes
a. Vitamin B12, B6, or folate deficiency.
b. Genetic factors such as MTHFR mutation.
c. Renal impairment or hypothyroidism.
Recommended Actions
- Consult a healthcare provider for further evaluation and testing.
- Consider dietary adjustments and supplementation under medical guidance.

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