I'm a bit concerned right now. Over the past few months, my follicular scans showed my endometrium thickness was in good range, over 6mm or even 7.75mm. But this month, it dropped to just 4.8mm. My thyroid profile looks normal with TSH, T3, and T4 levels, according to my doctor. But my antithyroglobulin and anti-TSH antibodies are really high. My doctor said I don't need meds for that, but when I went to an infertility center, they gave me Thyronorm to take every morning on an empty stomach. I'm worried if this condition is affecting my fertility or chances of getting pregnant. Could the thyroxine sodium be making my endometrium thinner? Should I even take it? Also, I'm curious if taking Estrogen Estradiol Valerate from day 5 of my period and Progesterone Duphaston from the 15th day will help thicken my endometrium and improve my chances of getting pregnant. What do you think?

Answered by 1 Apollo Doctors

Dr Dhankecha Dineshbhai

General Practitioner

MBBS
6+ Yrs

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Elevated anti-thyroglobulin and anti-TSH antibodies may indicate autoimmune thyroiditis, potentially affecting fertility and pregnancy; taking Thyronorm (thyroxine sodium) as prescribed by the infertility center may help regulate your thyroid function and improve fertility, despite your normal TSH, T3, and T4 levels; the medication might also contribute to the temporary thinning of your endometrium; to promote endometrial growth, your doctor's recommendation of Estradiol Valerate from Day 5 and Duphaston from Day 15 of your cycle may be beneficial, but closely monitor your endometrial thickness and adjust the treatment plan as needed.

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Answered 04/07/2025

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I'm on day 4 of my cycle and my doctor started me on Siphene 50mg because I had irregular egg sizes last month. Ive been taking it since day 2, but I noticed my period unexpectedly stopped around 3.5 days. Usually, it lasts at least 5 days. Could Siphene be the reason my bleeding stopped earlier this time? Id really like to understand what's going on.

Siphene may have caused a shorter or lighter period in your case, which can sometimes happen as a result of hormonal changes or adjustments. Its not typically known to stop menstrual bleeding altogether, but it can influence the menstrual cycle. If you're concerned, its best to check with your doctor, who may want to monitor your endometrial lining and overall response to the medication.