I'm a bit concerned right now. Over the past few months, my follicular scans showed my endometrium thickness was in good range, over 6mm or even 7.75mm. But this month, it dropped to just 4.8mm. My thyroid profile looks normal with TSH, T3, and T4 levels, according to my doctor. But my antithyroglobulin and anti-TSH antibodies are really high. My doctor said I don't need meds for that, but when I went to an infertility center, they gave me Thyronorm to take every morning on an empty stomach. I'm worried if this condition is affecting my fertility or chances of getting pregnant. Could the thyroxine sodium be making my endometrium thinner? Should I even take it? Also, I'm curious if taking Estrogen Estradiol Valerate from day 5 of my period and Progesterone Duphaston from the 15th day will help thicken my endometrium and improve my chances of getting pregnant. What do you think?

Answered by 1 Apollo Doctors

Dr Dhankecha Dineshbhai

General Practitioner

MBBS
6+ Yrs

Consult Now

Elevated anti-thyroglobulin and anti-TSH antibodies may indicate autoimmune thyroiditis, potentially affecting fertility and pregnancy; taking Thyronorm (thyroxine sodium) as prescribed by the infertility center may help regulate your thyroid function and improve fertility, despite your normal TSH, T3, and T4 levels; the medication might also contribute to the temporary thinning of your endometrium; to promote endometrial growth, your doctor's recommendation of Estradiol Valerate from Day 5 and Duphaston from Day 15 of your cycle may be beneficial, but closely monitor your endometrial thickness and adjust the treatment plan as needed.

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Answered 04/07/2025

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