I'm really concerned about something. So, my mom developed this boil on her neck about six months back, and apart from that, she didnt have any other symptoms. We decided to consult a doctor, who suggested a Mantoux test. But heres the thingthe lab technician seemed really new and injected the liquid deep inside her hand, not just under the top layer of skin. After three days, it turned red. The doctor then recommended TB treatment based on the result, even though she wasn't showing any other TB symptoms. With the lockdown kicking in, we couldn't start the treatment for three months. When things opened up, we went back to the doctor, and they suggested another Mantoux test since quite some time had passed. This time, at a different lab, the technician did it right on the outer layer, and it came back negative. Thankfully, the doctor said we didnt need to start any treatment. This whole experience has been pretty confusing, and I'm not sure what to think now. Can a Mantoux test be inaccurate sometimes, or could this have been a mistake due to the technique used?

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Dr Kareemulla Shaik

General Practitioner

MBBS
0+ Yrs

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do alternative test like CBNAAT

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Answered 04/07/2025

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Inaccuracy of the Mantoux Test:
- The Mantoux test can sometimes yield false positives or negatives.
- Factors like prior BCG vaccination or exposure to non-tuberculous mycobacteria can affect results.
Technique Factors:
- Proper administration and reading of the test are crucial.
- Errors in injection or measurement can lead to inaccurate results.
Reassurance for a 50-Year-Old Woman:
- Discuss results with a healthcare provider for accurate interpretation.
- Consider additional tests if results are inconclusive or unexpected.

Recommendation:

Follow up with a healthcare professional to discuss the results and next steps.

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Answered 10/09/2025

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