apollo
  • Male
  • 40 Years
  • 14/08/2025

I've been on these PPI meds for over a year now - dexlansoprazole 60mg daily, esomeprazole 40mg daily, and levosulpiride 75mg daily - but I'm still dealing with acid reflux, esophagitis, and gastritis. What are the long-term side effects of staying on PPIs this long? Is it safe to keep taking them beyond a year? Are there any surgical options that could help cure this instead? I can share my endoscopy report if needed.

Doctor 1

Answered by 1 Apollo Doctors

Long-term PPI use is generally safe but may cause low magnesium, B12 deficiency, and gut flora changes. Surgery (like Nissen) may help if you're not responding. Share endoscopy for detailed advice.

Dr. Dhankecha Suggests...

Consult a Gastroenterology/gi Medicine Specialist

Answered 14/08/2025

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Disclaimer: Answers on Apollo 247 are not intended to replace your doctor advice. Always seek help of a professional doctor in case of an medical emergency or ailment.