I've been on these PPI meds for over a year now - dexlansoprazole 60mg daily, esomeprazole 40mg daily, and levosulpiride 75mg daily - but I'm still dealing with acid reflux, esophagitis, and gastritis. What are the long-term side effects of staying on PPIs this long? Is it safe to keep taking them beyond a year? Are there any surgical options that could help cure this instead? I can share my endoscopy report if needed.

Answered by 1 Apollo Doctors

Dr Dhankecha Dineshbhai

General Practitioner

MBBS
6+ Yrs

Consult Now

Long-term PPI use is generally safe but may cause low magnesium, B12 deficiency, and gut flora changes. Surgery (like Nissen) may help if you're not responding. Share endoscopy for detailed advice.

Dr. Dhankecha Suggests...

Consult a Gastroenterology/gi Medicine Specialist

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Answered 14/08/2025

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I recently had an LFT done and I'm a bit concerned about the results. My AST (SGOT) is at 174 UL, my ALT (SGPT) at 296 UL, and GGTP at 46 UL, although all other LFT results are normal. Can you help me understand what might be causing these elevated levels and suggest what kind of treatment I should consider? Also, would a general physician be enough for this, or should I see a liver specialist?

consult Nephrologist

Answered by 1 Apollo Doctors

Can I live a normal life with Crohn's disease? I'm in college and dream of becoming a scientist, but I've heard this condition is considered a disability and might need lifelong surgeries. Will I ever be able to have a regular life? Feeling really down and could use some advice open to an online consultation.

Surgery opinion is advised at apollo hospital.

Answered by 1 Apollo Doctors

I've been dealing with constant diarrhea for the last couple of days, and even though I'm taking loperamide and using O.R.S., it hasn't stopped. Should I be worried? Is there anything else I can do to help stop it?

Persistent diarrhea despite taking loperamide and ORS warrants further attention; consider consulting a gastroenterologist or a primary care physician to rule out underlying causes like bacterial or viral infections, food poisoning, or inflammatory bowel disease; they may prescribe additional medications, such as antibiotics or anti-inflammatory agents, and recommend stool tests, blood work, or other diagnostic procedures to determine the underlying cause and develop an effective treatment plan.

Answered by 1 Apollo Doctors

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Disclaimer: Answers on Apollo 247 are not intended to replace your doctor advice. Always seek help of a professional doctor in case of an medical emergency or ailment.