Effective price: ₹2046
Above 10 years
The centromere is a chromosomal structure that binds two chromatids together. It acts as the link between a pair of sister chromatids or two identical copies born from the exact DNA replication.Centromere antibodies have a significant role in developing CREST syndrome.
The syndrome, also known as limited systemic scleroderma or limited systemic sclerosis, is characterised by a few different problems. The following conditions together characterise the CREST syndrome:
The Centromere IgG Antibody Test helps detect CREST syndrome. The centromere AB IgG s test is conducted on the blood serum with the help of a blood sample. You can book the test from Apollo 24|7 at a very reasonable price and have the phlebotomist visit you to collect the sample.
The serum must be separated from the blood sample within two hours of collection and then refrigerated. Any sample that is contaminated, haemolysed, consists of plasma, or has lipemic specimens will not deduce accurate results.
The centromere antibodies are identified by their own distinctive patterns of nuclear staining on the cell substrates in the fluorescent antinuclear antibody test (ANA).
The Centromere IgG Antibody Test (centromere AB IgG s) is highly useful for evaluating the conditions, signs, and symptoms of systemic sclerosis. A positive result in the centromere AB IgG s test (≥1.0 U) denotes the possibility of CREST syndrome at a very early stage.
Although CREST syndrome and scleroderma in general, is not curable, it can have a favourable prognosis and allow the patient to live longer. Other than CREST syndrome, the Centromere IgG antibody test also detects the more common clinical arthralgia and less occurring features, like stiffness, arthritis, and flexion contractures.
Why should Apollo be your preferred healthcare partner?
The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results