Protein electrophoresis is a test used for measuring specific proteins in the blood.
The protein electrophoresis test is often used to detect M proteins. The test may be advised if the person experiences symptoms like unexplained weight loss, bone pain or frequent fractures, fatigue, weakness, constipation, excessive thirst, nausea.
The test is used for diagnosis of few cancers (e.g. Multiple Myeloma), Waldenström macroglobulinemia, monoclonal gammopathy of undetermined significance (MGUS), primary amyloidosis, few liver and kidney diseases, certain autoimmune diseases, malnutrition, bone pain, unexplained peripheral neuropathy, new-onset anaemia.
Frequently asked questions
How is the blood sample taken?
To take the blood sample, a tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins and it becomes easy to collect the blood. The skin is cleaned before inserting the needle in the vein in order to prevent bacteria from entering. Needle is inserted into the vein of the arm and the blood sample is collected in the vacutainer.
What are the symptoms of high protein?
Pain in your bones, numbness or tingling in your hands, feet, or legs, loss of appetite, weight loss, excessive thirst, frequent infections, etc., are some of the symptoms of high protein.
What are the major group of proteins in blood?
The major group of proteins in blood are albumin and globulin. These two groups of albumin and globulin can be separated into five smaller groups like albumin, alpha-1 globulin, alpha-2 globulin, beta globulin, gamma globulin.
What conditions affect the test results?
High levels of lipids, iron deficiency anaemia, pregnancy and few medication like corticosteroids, insulin, cholesterol-lowering medicines (statins), and birth control pills, etc., may affect the test results.
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