Typhoid Test

Typhidot - IgG

Test Overview

The Typhidot - IgG test plays a vital role in diagnosing Typhoid fever, a systemic infection caused by the bacterium Salmonella Typhi. Typhoid fever is a serious illness spread through contaminated food and water, leading to symptoms like sustained fever, fatigue, abdominal pain, and sometimes rash.

This test specifically detects Immunoglobulin G (IgG) antibodies produced by the body's immune system in response to an infection with Salmonella Typhi. While IgM antibodies typically indicate an acute or recent infection, the presence of IgG antibodies usually suggests a past exposure to Salmonella Typhi, a convalescent (recovering) stage of an acute infection, or in some cases, a chronic carrier state. This article explains the purpose, target groups, test components, interpretation, preparation, and booking options for the Typhidot - IgG test.

Purpose of Typhidot - IgG Test

Understanding the purpose of the Typhidot - IgG test is crucial for assessing an individual's exposure to Salmonella Typhi, the bacterium responsible for Typhoid fever. Here's why this test is recommended:

• Confirming Past Typhoid Exposure: The primary purpose of the Typhidot - IgG test is to detect Immunoglobulin G (IgG) antibodies against Salmonella Typhi antigens. The presence of these antibodies typically indicates a past infection with Salmonella Typhi or prior exposure to the bacterium.
• Aiding in the Diagnosis of Current Infection (Late Stage or Convalescent): While IgM antibodies are crucial for early acute diagnosis, IgG antibodies appear later in the course of an acute Typhoid infection (usually 10-14 days after symptom onset) and persist for a longer period. Therefore, detecting IgG, especially in conjunction with clinical symptoms and other tests (like Typhidot - IgM or blood culture), can help in diagnosing an active infection in its later stages or confirming a convalescent (recovering) phase.
• Identifying Chronic Carriers: In some cases, the presence of IgG antibodies, particularly persistently high levels without acute symptoms, can suggest a chronic carrier state of Salmonella Typhi, where an individual harbors the bacteria without active disease but can transmit it.
• Epidemiological Surveillance: The test can be used in public health studies to determine the prevalence of past Typhoid exposure within a population, aiding in understanding disease patterns.

The Typhidot - IgG test is thus an important tool for understanding an individual's immune history related to Typhoid, complementing other diagnostic methods for a comprehensive assessment.

Price of Typhidot - IgG Test

The cost of the Typhidot - IgG test can differ based on several factors, including location, test methodology, and additional services. Being aware of these elements can help you plan better before booking the test.

• Location: The price of the Typhidot - IgG test may vary depending on the city or region. Urban diagnostic centers often charge more than those in smaller towns due to higher operational costs.
• Test Methodology: Labs using advanced or high-sensitivity techniques like CLIA or ELISA may charge a premium compared to basic testing methods, as they offer greater accuracy.
• Home Sample Collection: If you opt for home collection, there might be a nominal additional fee, though some providers offer this service free of charge or as part of a package.
• Lab Accreditation: NABL- or CAP-accredited labs often price tests slightly higher because of their adherence to strict quality standards and use of sophisticated equipment.

Who Should Get Typhidot - IgG Test?

A Typhidot - IgG test is a specific blood test primarily recommended for individuals suspected of having Typhoid fever, or to determine past exposure to the Salmonella Typhi bacterium, especially in endemic areas or after relevant travel. Doctors may recommend this test in the following situations:
Individuals with Suspected Typhoid Fever (Late Stage or Convalescent): Those exhibiting characteristic symptoms of Typhoid such as prolonged, high fever, headache, abdominal pain, fatigue, or constipation/diarrhea, particularly if these symptoms have lasted for more than 7-10 days, as IgG antibodies appear later in the infection.

• Individuals with Prolonged or Unexplained Fever: Since Typhoid infection can manifest as a persistent fever without other clear causes, people experiencing these symptoms where Typhoid is a possibility may benefit from this test to assess for prior exposure or a resolving infection.
• Assessment of Past Exposure in Specific Populations: For individuals who may have been exposed to Salmonella Typhi in the past, such as those with a history of living in or traveling to endemic regions, the Typhidot - IgG test helps in confirming previous infection.
• Patients Undergoing Differential Diagnosis for Enteric Fevers: When clinicians need to differentiate Typhoid infection from other causes of similar prolonged febrile symptoms (like malaria, dengue, paratyphoid fever, or other bacterial infections), this test can provide evidence of Typhoid exposure.
• Investigation of Chronic Carrier States: In certain public health investigations or for individuals with recurrent fever and a history of Typhoid, the presence of IgG antibodies can contribute to the assessment of a chronic carrier state, though other tests (like stool culture) are crucial for definitive confirmation.
  Report Interpretation

Understanding the Typhidot - IgG Test Report

A clear understanding of your Typhidot - IgG test report is essential for accurate assessment and management of your Dengue infection status. This test primarily measures the presence of Immunoglobulin G (IgG) antibodies to Salmonella Typhi to determine if you have had a past Typhoid infection or are in the later stages of a current one.

• Positive Result: A positive Typhidot - IgG result typically indicates that the individual has had a past Typhoid infection or is in the later/convalescent stage of a current infection. It can also, in some contexts, suggest a chronic carrier state of Salmonella Typhi. It does not primarily confirm an acute, early-stage infection (for which IgM or culture would be more indicative).
• Negative Result: A negative Typhidot - IgG result suggests no detectable past Typhoid infection or no detectable IgG antibodies at the time of testing. It might also occur if the test is performed very early in the course of an acute infection before IgG antibodies have developed. It does not rule out an acute infection if tested too early or if only IgM or culture are positive.
• Equivocal or Borderline Result: Sometimes, antibody levels hover around the cut-off value, resulting in an inconclusive outcome. Repeat testing after 1-2 weeks or additional diagnostic tests (like Typhidot - IgM, blood culture, or stool culture) may be necessary for a definitive diagnosis.
• Clinical Correlation Required: Test results must always be interpreted alongside clinical symptoms, patient history (e.g., travel, exposure), and other laboratory findings (like blood cultures or Typhidot - IgM results). For example, the presence of IgG antibodies without IgM typically suggests past infection or immunity, while concurrent IgM and IgG may point to a recent or ongoing infection.
• Cross-Reactivity and False Positives: Rarely, cross-reactivity with antibodies from other Salmonella serovars, other bacterial infections, or non-specific immune responses can cause false positive results. A thorough patient history and confirmatory tests are crucial to avoid misdiagnosis.

Preparation and Procedure of Typhidot - IgG

Before undergoing a Typhidot - IgG test, it is essential to understand the preparation required and the steps involved to ensure accurate results.

• No Special Preparation Needed: Patients do not need to fast or avoid medications before undergoing the Typhidot - IgG test. Routine daily activities can continue uninterrupted.
• Blood Sample Collection: A healthcare professional will draw a small sample of venous blood, usually from a vein in your arm. The procedure is quick, minimally painful, and safe.
• Sample Processing: The blood sample is sent to a certified laboratory. The serum is separated from the blood and then tested using ELISA or other immunoassay platforms to specifically detect IgG antibodies against Salmonella Typhi antigens.
• Turnaround Time: Test results are typically available within 24 to 48 hours, depending on laboratory capacity and processing speed.
• Informing Your Doctor: It’s important to inform your healthcare provider about recent illnesses (especially fevers), any travel history, vaccinations, or current medications, as these can influence test interpretation.

How to Book Typhidot - IgG Test at Apollo 24|7?

• Convenient Online Booking: Apollo 24|7 offers a seamless platform where you can easily schedule your Typhidot - IgG test online via their website or mobile app. You can select the test, provide details, and choose a convenient time slot.
• Home Sample Collection: For added convenience, Apollo 24|7 arranges for trained phlebotomists to collect your blood sample at home, ensuring a hassle-free experience without the need to visit a lab or hospital.
• Affordable Pricing and Offers: Apollo 24|7 provides competitive pricing for the Typhidot - IgG test, often with discounts and promotional offers. Transparent pricing ensures no hidden costs.
• Digital Report Delivery: Once processed, your test report will be securely uploaded to your Apollo 24|7 account. You can access, download, and share your results instantly from anywhere.
• Consultation Services: Apollo 24|7 also offers access to qualified doctors who can help interpret your Typhidot - IgG test results and guide you on the next steps or treatment options if needed.
• Reliable Customer Support: If you have any questions or need assistance with booking or sample collection, Apollo 24|7’s customer support is available round the clock to provide help.