Dr. Prof. Vijay Agarwal

Strong emphasis on translational and precision oncology, linking molecular mechanisms with clinical outcomes to improve cancer treatment strategies. Extensive research in malignant pleural mesothelioma, focusing on EGFR, PTEN, lipoxygenase pathways, COX-2 inhibition, mTOR signaling, and mechanisms of therapeutic resistance. Significant contributions to proteomics-based biomarker discovery, using antibody microarrays, 2-DE, and MALDI-TOF/TOF technologies. Identification of 14-3-3 proteins and tBID as potential predictive and resistance biomarkers in neoadjuvant chemotherapy for luminal and ER-positive breast cancer. Critical evaluation of EGFR as a therapeutic target across multiple malignancies, including head and neck cancers and mesothelioma. Clinical research in breast cancer management, including outcomes of primary letrozole therapy in elderly patients and HER2-directed treatments in metastatic disease. Contributions to oncology decision-making tools and clinical endpoints, including surrogate endpoints supporting overall survival and use of Adjuvant! Online. Active role in advancing shared decision-making, ethics, and medicolegal aspects of high-quality cancer care in the Indian healthcare context. Research addressing rare tumors and unusual clinical presentations, such as primary hepatic neuroendocrine tumors and rare metastatic sites in germ cell tumors. Involvement in genetic oncology, including genotype–phenotype correlation in Li-Fraumeni syndrome and the importance of genetic counseling. Focus on biomarker-driven personalization of therapy, studying p53, PTEN, HER2, EGFR, and inflammatory markers like NLR and PLR. Contributions to head and neck oncology, including biomarker expression studies and prognostic marker evaluation. Strong presence at national and international oncology conferences, with posters and oral presentations at ESMO, ECCO, IMIG, NCRI, SABCS, and BTG meetings. Interdisciplinary collaboration across medical oncology, surgical oncology, pathology, radiology, molecular biology, and palliative care. A sustained and impactful academic career spanning over a decade, bridging laboratory research, clinical practice, education, and policy in oncology.